STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERJ93979.1Sigma-70 region 2; KEGG: btk:BT9727_3349 3.4e-09 RNA polymerase ECF-type sigma factor K03088; Belongs to the sigma-70 factor family. ECF subfamily. (167 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.803
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.795
ERJ93978.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.773
ERJ93977.1
Hypothetical protein.
       0.727
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.698
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.698
ERJ96255.1
Hypothetical protein; KEGG: lif:LINJ_16_1550 1.2e-10 putative kinesin; Psort location: Cytoplasmic, score: 7.50.
    
   0.634
ERJ95232.1
Sigma-70 region 2; KEGG: cbo:CBO1625 3.5e-16 RNA polymerase factor sigma-70; Psort location: Cytoplasmic, score: 7.50; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.616
ERJ95001.1
Phage tail component protein; KEGG: ral:Rumal_1816 2.4e-143 serine/threonine protein kinase with PASTA sensor(s); K08884 serine/threonine protein kinase, bacterial; Psort location: CytoplasmicMembrane, score: 9.51.
   
 
 0.479
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
 
 0.465
Your Current Organism:
Ruminococcus callidus
NCBI taxonomy Id: 411473
Other names: R. callidus ATCC 27760, Ruminococcus callidus ATCC 27760
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