STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP27577.1Hydrolase, NUDIX family; KEGG: aae:aq_158 1.2e-16 apfA; AP4A hydrolase K03574; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. (166 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
    
 0.833
pyk
Pyruvate kinase; KEGG: tte:TTE1815 3.7e-173 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score:8.87.
  
 
  0.819
EDP25561.1
Diguanylate cyclase (GGDEF) domain protein; KEGG: ava:Ava_1777 6.3e-30 metal dependent phosphohydrolase, HD region with response regulator receiver modulation K07814; COG: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; Psort location: CytoplasmicMembrane, score:7.63.
  
 
  0.817
EDP26960.1
Putative nicotinamide-nucleotide adenylyltransferase; KEGG: eca:ECA0463 6.6e-32 nadR, nadI; transcriptional regulator of NAD metabolism K00952:K06210:K06211; COG: COG3172 Predicted ATPase/kinase involved in NAD metabolism; Psort location: Cytoplasmic, score:8.87.
  
 
 0.813
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.813
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
 0.803
folE
GTP cyclohydrolase I; KEGG: cac:CAC3626 3.1e-66 mtrA; GTP cyclohydrolase I K01495; COG: COG0302 GTP cyclohydrolase I; Psort location: Cytoplasmic, score:8.87.
  
 
 0.802
EDP26081.1
Competence/damage-inducible domain protein CinA; KEGG: btl:BALH_2918 0.0084 vanY; D-alanyl-D-alanine carboxypeptidase, N-terminal region K01286; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score:8.87; Belongs to the CinA family.
    
  0.802
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
    
  0.792
EDP27561.1
RelA/SpoT domain protein; KEGG: ctc:CTC00336 2.8e-65 GTP pyrophosphokinase K07816; COG: COG2357 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.87.
  
  
  0.779
Your Current Organism:
Coprococcus eutactus
NCBI taxonomy Id: 411474
Other names: C. eutactus ATCC 27759, Coprococcus eutactus ATCC 27759
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