STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP27141.1Hydrolase, NUDIX family; KEGG: lsa:LSA1593 4.1e-16 putative nucleotide diphosphate hydrolase, NUDIX family K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score:8.87. (203 aa)    
Predicted Functional Partners:
nnrD
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
 0.942
prs
Ribose-phosphate diphosphokinase; KEGG: cac:CAC0819 8.8e-101 phosphoribosylpyrophosphate synthetase K00948; COG: COG0462 Phosphoribosylpyrophosphate synthetase; Psort location: Cytoplasmic, score:8.87; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 
 0.927
EDP27140.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: cpr:CPR_1841 2.0e-158 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score:8.87.
  
 
  0.908
ribA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
  0.846
EDP27607.1
Hydrolase, NUDIX family; KEGG: tte:TTE1310 1.0e-26 mutT2; NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score:8.87; Belongs to the Nudix hydrolase family.
  
  
 
0.818
EDP27139.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: cpe:CPE1873 1.5e-144 manB; probable phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score:8.87.
  
 
  0.813
pyk
Pyruvate kinase; KEGG: tte:TTE1815 3.7e-173 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score:8.87.
 
  
  0.807
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.801
EDP27138.1
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: bca:BCE_5058 1.4e-148 phosphoglucomutase/phosphomannomutase family protein K01835:K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score:8.87.
  
 
  0.789
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.785
Your Current Organism:
Coprococcus eutactus
NCBI taxonomy Id: 411474
Other names: C. eutactus ATCC 27759, Coprococcus eutactus ATCC 27759
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