Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDP26813.1Histidine triad domain protein; KEGG: lsa:LSA0628 3.0e-29 putative diadenosine polyphosphate hydrolase K02503; COG: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. (138 aa)    
Predicted Functional Partners:
EDP26210.1
Phosphoribulokinase/uridine kinase family protein; KEGG: tte:TTE1778 1.0e-74 udk; uridine kinase K00876; COG: COG0572 Uridine kinase; Psort location: Cytoplasmic, score:8.87.
   
  0.829
cobB
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
 
  
  0.797
lysS
lysine--tRNA ligase; KEGG: tte:TTE2372 2.3e-154 lysU; lysyl-tRNA synthetase class II K04567; COG: COG1190 Lysyl-tRNA synthetase (class II); Psort location: Cytoplasmic, score:10.00; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.785
glnA-2
KEGG: chy:CHY_0704 6.1e-164 glnA1; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.98.
   
   0.783
EDP26812.1
Protein TraX; COG: NOG30164 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.99.
       0.545
EDP27087.1
Putative thioredoxin-disulfide reductase; KEGG: bha:BH3571 2.0e-62 trxB; thioredoxin reductase (NADPH) K00384; COG: COG0492 Thioredoxin reductase; Psort location: Cytoplasmic, score:9.65.
 
     0.425
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
   
 
 0.405
Your Current Organism:
Coprococcus eutactus
NCBI taxonomy Id: 411474
Other names: C. eutactus ATCC 27759, Coprococcus eutactus ATCC 27759
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.