Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemZCoproporphyrinogen dehydrogenase HemZ; KEGG: ctc:CTC02195 5.8e-88 oxygen-independent coproporphyrinogen III oxidase K02495; COG: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Psort location: Cytoplasmic, score:9.98. (521 aa)    
Predicted Functional Partners:
EDP26819.1
HDIG domain protein; KEGG: ava:Ava_1777 1.8e-17 metal dependent phosphohydrolase, HD region with response regulator receiver modulation K07814; COG: COG2206 HD-GYP domain; Psort location: Cytoplasmic, score:8.87.
       0.816
EDP26821.1
Metallo-beta-lactamase domain protein; KEGG: ctc:CTC02196 4.3e-37 hydroxyacylglutathione hydrolase K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases.
     
 0.672
aspS
aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.636
argS
arginine--tRNA ligase; KEGG: cpf:CPF_1915 2.7e-161 argS; arginyl-tRNA synthetase K01887; COG: COG0018 Arginyl-tRNA synthetase; Psort location: Cytoplasmic, score:9.98.
   
    0.561
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.560
EDP26823.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
       0.532
recJ
KEGG: cac:CAC2232 8.7e-133 recJ; SsDNA exonuclease, RecJ K07462; COG: COG0608 Single-stranded DNA-specific exonuclease; Psort location: Cytoplasmic, score:8.87.
  
    0.521
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 6.4e-82 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score:8.87.
  
  
 0.510
EDP26794.1
PAS domain S-box protein; KEGG: mma:MM0260 1.8e-14 putative sensory transduction protein kinase; COG: COG2202 FOG: PAS/PAC domain; Psort location: Cytoplasmic, score:8.87.
  
  
 0.507
EDP26822.1
COG: COG3401 Fibronectin type 3 domain-containing protein.
       0.506
Your Current Organism:
Coprococcus eutactus
NCBI taxonomy Id: 411474
Other names: C. eutactus ATCC 27759, Coprococcus eutactus ATCC 27759
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