Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDP26528.1Peptidase, S54 family; KEGG: ddi:DDB0218357 7.6e-14 hypothetical protein K08641; COG: COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); Psort location: CytoplasmicMembrane, score:9.99. (333 aa)    
Predicted Functional Partners:
EDP26529.1
Hypothetical protein; COG: COG0393 Uncharacterized conserved protein; Psort location: Cytoplasmic, score:8.87.
 
     0.716
EDP24875.1
KEGG: bce:BC4687 4.9e-36 N-acetylmuramoyl-L-alanine amidase K01446; COG: COG0860 N-acetylmuramoyl-L-alanine amidase.
  
 
   0.683
EDP26527.1
Hypothetical protein; KEGG: mpe:MYPE6470 2.8e-33 parC; DNA topoisomerase IV subunit A K02621; COG: COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; Psort location: Extracellular, score:7.62.
  
    0.667
EDP25336.1
KEGG: lsa:LSA0862 3.1e-26 N-acetylmuramoyl-L-alanine amidase precursor (cell wall hydrolase) (autolysin) K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase.
    
   0.643
EDP26526.1
Hypothetical protein; KEGG: ddi:DDB0167703 1.1e-32 hypothetical protein K01971; COG: KOG1181 FOG: Low-complexity; Psort location: Extracellular, score:7.62.
       0.539
EDP27537.1
KEGG: bsu:BG11681 1.5e-27 yqgN; similar to 5-formyltetrahydrofolate cyclo-ligase K01934; COG: COG0212 5-formyltetrahydrofolate cyclo-ligase; Psort location: Cytoplasmic, score:8.87.
  
  
 0.484
folA
KEGG: bce:BC2192 8.4e-25 dihydrofolate reductase K00287; COG: COG0262 Dihydrofolate reductase; Psort location: Cytoplasmic, score:8.87.
       0.459
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.418
EDP24936.1
SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 1.3e-53 membrane protease subunits, stomatin/prohibitin homologs K01423; COG: COG0330 Membrane protease subunits, stomatin/prohibitin homologs.
   
 0.415
EDP27753.1
KEGG: tte:TTE2424 1.8e-22 amiC2; N-acetylmuramoyl-L-alanine amidase K01448; COG: COG0860 N-acetylmuramoyl-L-alanine amidase; Psort location: Cytoplasmic, score:8.87.
   
   0.414
Your Current Organism:
Coprococcus eutactus
NCBI taxonomy Id: 411474
Other names: C. eutactus ATCC 27759, Coprococcus eutactus ATCC 27759
Server load: low (12%) [HD]