Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDP26399.1Siroheme synthase domain protein; KEGG: aae:aq_1237 1.6e-23 cysG; precorrin-2 oxidase. (212 aa)    
Predicted Functional Partners:
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: cno:NT01CX_0261 6.4e-82 uroporphyrinogen III synthase/methyltransferase K00589; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score:8.87.
 
 0.999
EDP27092.1
Siroheme synthase domain protein; KEGG: nmu:Nmul_A2313 1.4e-24 uroporphyrin-III C-methyltransferase K02302:K02303:K02304; COG: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); Psort location: Cytoplasmic, score:8.87.
  
  
 
0.923
hemL
KEGG: gme:Gmet_3356 2.2e-127 glutamate-1-semialdehyde-2,1-aminomutase K01845; COG: COG0001 Glutamate-1-semialdehyde aminotransferase; Psort location: Cytoplasmic, score:8.87.
   
 0.771
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.717
EDP26398.1
Hypothetical protein.
       0.701
hemB
Porphobilinogen synthase; KEGG: chy:CHY_1210 3.7e-109 hemB; porphobilinogen synthase K01698; COG: COG0113 Delta-aminolevulinic acid dehydratase; Psort location: Cytoplasmic, score:8.87; Belongs to the ALAD family.
 
   
 0.650
rimP
Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
 
     0.575
EDP26400.1
Putative peptidoglycan binding domain protein; KEGG: bsu:BG10962 4.3e-05 xlyA; N-acetylmuramoyl-L-alanine amidase, peptidoglycan hydrolase (PBSX prophage-mediated lysis) K01447; COG: NOG36567 non supervised orthologous group.
       0.542
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
       0.482
Your Current Organism:
Coprococcus eutactus
NCBI taxonomy Id: 411474
Other names: C. eutactus ATCC 27759, Coprococcus eutactus ATCC 27759
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