| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDP25213.1 | nfo | COPEUT_02708 | COPEUT_02100 | 8-oxoguanine DNA-glycosylase (ogg); KEGG: tte:TTE0574 4.9e-59 alkA; 3-Methyladenine DNA glycosylase K03660; COG: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Psort location: Cytoplasmic, score:8.87. | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.720 |
| EDP25213.1 | nth | COPEUT_02708 | COPEUT_02392 | 8-oxoguanine DNA-glycosylase (ogg); KEGG: tte:TTE0574 4.9e-59 alkA; 3-Methyladenine DNA glycosylase K03660; COG: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Psort location: Cytoplasmic, score:8.87. | Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.529 |
| EDP25213.1 | polA | COPEUT_02708 | COPEUT_00189 | 8-oxoguanine DNA-glycosylase (ogg); KEGG: tte:TTE0574 4.9e-59 alkA; 3-Methyladenine DNA glycosylase K03660; COG: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Psort location: Cytoplasmic, score:8.87. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.586 |
| EDP25213.1 | xth | COPEUT_02708 | COPEUT_00176 | 8-oxoguanine DNA-glycosylase (ogg); KEGG: tte:TTE0574 4.9e-59 alkA; 3-Methyladenine DNA glycosylase K03660; COG: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Psort location: Cytoplasmic, score:8.87. | Exodeoxyribonuclease III; KEGG: cac:CAC0222 3.8e-107 exoA; exodeoxyribonuclease (exoA) K01142; COG: COG0708 Exonuclease III; Psort location: Cytoplasmic, score:9.98. | 0.878 |
| EDP25724.1 | nfo | COPEUT_02099 | COPEUT_02100 | Glyoxalase family protein; KEGG: bur:Bcep18194_C7651 0.00021 glyoxalase/bleomycin resistance protein/dioxygenase K00446; COG: COG0346 Lactoylglutathione lyase and related lyases. | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.460 |
| nfo | EDP25213.1 | COPEUT_02100 | COPEUT_02708 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 8-oxoguanine DNA-glycosylase (ogg); KEGG: tte:TTE0574 4.9e-59 alkA; 3-Methyladenine DNA glycosylase K03660; COG: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Psort location: Cytoplasmic, score:8.87. | 0.720 |
| nfo | EDP25724.1 | COPEUT_02100 | COPEUT_02099 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Glyoxalase family protein; KEGG: bur:Bcep18194_C7651 0.00021 glyoxalase/bleomycin resistance protein/dioxygenase K00446; COG: COG0346 Lactoylglutathione lyase and related lyases. | 0.460 |
| nfo | nth | COPEUT_02100 | COPEUT_02392 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.859 |
| nfo | polA | COPEUT_02100 | COPEUT_00189 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.531 |
| nfo | recU | COPEUT_02100 | COPEUT_00265 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.438 |
| nfo | topA | COPEUT_02100 | COPEUT_03033 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.436 |
| nfo | ung | COPEUT_02100 | COPEUT_02513 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.838 |
| nfo | xth | COPEUT_02100 | COPEUT_00176 | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Exodeoxyribonuclease III; KEGG: cac:CAC0222 3.8e-107 exoA; exodeoxyribonuclease (exoA) K01142; COG: COG0708 Exonuclease III; Psort location: Cytoplasmic, score:9.98. | 0.847 |
| nth | EDP25213.1 | COPEUT_02392 | COPEUT_02708 | Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 8-oxoguanine DNA-glycosylase (ogg); KEGG: tte:TTE0574 4.9e-59 alkA; 3-Methyladenine DNA glycosylase K03660; COG: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Psort location: Cytoplasmic, score:8.87. | 0.529 |
| nth | nfo | COPEUT_02392 | COPEUT_02100 | Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.859 |
| nth | polA | COPEUT_02392 | COPEUT_00189 | Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.721 |
| nth | ung | COPEUT_02392 | COPEUT_02513 | Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.623 |
| nth | xth | COPEUT_02392 | COPEUT_00176 | Putative endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | Exodeoxyribonuclease III; KEGG: cac:CAC0222 3.8e-107 exoA; exodeoxyribonuclease (exoA) K01142; COG: COG0708 Exonuclease III; Psort location: Cytoplasmic, score:9.98. | 0.983 |
| polA | EDP25213.1 | COPEUT_00189 | COPEUT_02708 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 8-oxoguanine DNA-glycosylase (ogg); KEGG: tte:TTE0574 4.9e-59 alkA; 3-Methyladenine DNA glycosylase K03660; COG: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; Psort location: Cytoplasmic, score:8.87. | 0.586 |
| polA | nfo | COPEUT_00189 | COPEUT_02100 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.531 |
