Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
murE-2UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; KEGG: lsl:LSL_0016 1.0e-74 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysine ligase K05362; COG: COG0769 UDP-N-acetylmuramyl tripeptide synthase; Psort location: Cytoplasmic, score:8.87; Belongs to the MurCDEF family. MurE subfamily. (507 aa)    
Predicted Functional Partners:
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 0.997
murD
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
 
 0.983
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
  
 
0.924
EDP25611.1
CobB/CobQ-like protein; KEGG: lsl:LSL_0587 1.1e-10 cobyric acid synthase K01957; COG: COG3442 Predicted glutamine amidotransferase; Psort location: Cytoplasmic, score:8.87.
 
 
 0.829
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
 0.816
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.784
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
   
 0.760
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
 
  
 0.690
EDP24956.1
Penicillin-binding protein, transpeptidase domain protein; KEGG: gsu:GSU3075 1.1e-65 penicillin-binding protein K03587; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score:9.83.
 
  
 0.611
EDP24957.1
Penicillin-binding protein, transpeptidase domain protein; KEGG: tte:TTE1916 2.2e-81 ftsI4; Cell division protein FtsI/penicillin-binding protein 2 K03587; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score:9.49.
 
  
 0.579
Your Current Organism:
Coprococcus eutactus
NCBI taxonomy Id: 411474
Other names: C. eutactus ATCC 27759, Coprococcus eutactus ATCC 27759
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