Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hflB-3ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (629 aa)    
Predicted Functional Partners:
EDP24936.1
SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 1.3e-53 membrane protease subunits, stomatin/prohibitin homologs K01423; COG: COG0330 Membrane protease subunits, stomatin/prohibitin homologs.
   
 0.831
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.759
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.723
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.722
rplQ
COG: COG0203 Ribosomal protein L17; Psort location: Cytoplasmic, score:8.87.
   
 
 0.717
rpsH
Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
   0.715
rpmJ
COG: COG0257 Ribosomal protein L36; Psort location: Cytoplasmic, score:8.87; Belongs to the bacterial ribosomal protein bL36 family.
   
 
 0.712
rpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.701
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.699
rpmA
COG: COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
  
   0.690
Your Current Organism:
Coprococcus eutactus
NCBI taxonomy Id: 411474
Other names: C. eutactus ATCC 27759, Coprococcus eutactus ATCC 27759
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