| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDP24932.1 | ilvD | COPEUT_02870 | COPEUT_03015 | Aconitase domain protein; KEGG: ecp:ECP_0784 4.6e-246 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score:9.98. | KEGG: chy:CHY_0516 1.9e-192 ilvD; dihydroxy-acid dehydratase K01687; COG: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.619 |
| EDP24932.1 | leuB | COPEUT_02870 | COPEUT_03014 | Aconitase domain protein; KEGG: ecp:ECP_0784 4.6e-246 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score:9.98. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.868 |
| ilvA | ilvB | COPEUT_00200 | COPEUT_00134 | KEGG: fnu:FN1411 1.5e-112 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | 0.950 |
| ilvA | ilvB-2 | COPEUT_00200 | COPEUT_03017 | KEGG: fnu:FN1411 1.5e-112 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | Acetolactate synthase, large subunit, biosynthetic type; KEGG: cac:CAC3169 5.2e-174 ilvB; acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | 0.952 |
| ilvA | ilvD | COPEUT_00200 | COPEUT_03015 | KEGG: fnu:FN1411 1.5e-112 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | KEGG: chy:CHY_0516 1.9e-192 ilvD; dihydroxy-acid dehydratase K01687; COG: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.841 |
| ilvA | ilvN | COPEUT_00200 | COPEUT_00133 | KEGG: fnu:FN1411 1.5e-112 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | KEGG: gme:Gmet_1261 2.4e-27 acetolactate synthase, small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.943 |
| ilvA | ilvN-2 | COPEUT_00200 | COPEUT_00185 | KEGG: fnu:FN1411 1.5e-112 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | KEGG: mta:Moth_2257 1.3e-37 acetolactate synthase, small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score:8.87. | 0.943 |
| ilvA | leuB | COPEUT_00200 | COPEUT_03014 | KEGG: fnu:FN1411 1.5e-112 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.963 |
| ilvA | leuD | COPEUT_00200 | COPEUT_03013 | KEGG: fnu:FN1411 1.5e-112 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.406 |
| ilvB | ilvA | COPEUT_00134 | COPEUT_00200 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | KEGG: fnu:FN1411 1.5e-112 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | 0.950 |
| ilvB | ilvB-2 | COPEUT_00134 | COPEUT_03017 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | Acetolactate synthase, large subunit, biosynthetic type; KEGG: cac:CAC3169 5.2e-174 ilvB; acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | 0.908 |
| ilvB | ilvD | COPEUT_00134 | COPEUT_03015 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | KEGG: chy:CHY_0516 1.9e-192 ilvD; dihydroxy-acid dehydratase K01687; COG: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.937 |
| ilvB | ilvN | COPEUT_00134 | COPEUT_00133 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | KEGG: gme:Gmet_1261 2.4e-27 acetolactate synthase, small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit. | 0.998 |
| ilvB | ilvN-2 | COPEUT_00134 | COPEUT_00185 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | KEGG: mta:Moth_2257 1.3e-37 acetolactate synthase, small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score:8.87. | 0.995 |
| ilvB | leuA | COPEUT_00134 | COPEUT_02511 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | Putative 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.864 |
| ilvB | leuB | COPEUT_00134 | COPEUT_03014 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.973 |
| ilvB | leuC | COPEUT_00134 | COPEUT_03010 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.507 |
| ilvB | leuD | COPEUT_00134 | COPEUT_03013 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.593 |
| ilvB-2 | ilvA | COPEUT_03017 | COPEUT_00200 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: cac:CAC3169 5.2e-174 ilvB; acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | KEGG: fnu:FN1411 1.5e-112 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. | 0.952 |
| ilvB-2 | ilvB | COPEUT_03017 | COPEUT_00134 | Acetolactate synthase, large subunit, biosynthetic type; KEGG: cac:CAC3169 5.2e-174 ilvB; acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | Acetolactate synthase, large subunit, biosynthetic type; KEGG: mma:MM0670 3.4e-154 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score:8.87. | 0.908 |