Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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codYGTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. (254 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.689
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
    0.576
EDP25097.1
Hypothetical protein; KEGG: mpe:MYPE6470 3.3e-12 parC; DNA topoisomerase IV subunit A K02621; COG: KOG1181 FOG: Low-complexity; Psort location: Cytoplasmic, score:8.87.
       0.563
EDP27816.1
Hypothetical protein; KEGG: bcl:ABC3097 8.6e-16 beta-N-acetylglucosaminidase K01227; COG: COG5651 PPE-repeat proteins; Psort location: Extracellular, score:7.62.
  
     0.547
EDP25207.1
Putative RNA polymerase sigma-H factor; KEGG: reh:H16_B0256 1.8e-05 fliA; DNA-directed RNA polymerase sigma subunit / flagellum specific K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score:8.87; Belongs to the sigma-70 factor family.
  
   
 0.545
whiA
Hypothetical protein; Involved in cell division and chromosome segregation.
  
     0.525
EDP25098.1
Hypothetical protein; KEGG: cal:orf19.4072 5.9e-18 HYR10; similar to cell surface flocculin K01186; COG: COG5295 Autotransporter adhesin; Psort location: Cellwall, score:9.18.
       0.523
sepF
Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
   
  
 0.519
EDP26338.1
Hypothetical protein; Psort location: Cytoplasmic, score:8.87.
  
     0.519
EDP25313.1
Putative sporulation protein YyaC; COG: NOG10995 non supervised orthologous group.
  
     0.501
Your Current Organism:
Coprococcus eutactus
NCBI taxonomy Id: 411474
Other names: C. eutactus ATCC 27759, Coprococcus eutactus ATCC 27759
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