STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (190 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
 
 
 0.976
EEU96861.1
Hypothetical protein; KEGG: pae:PA1770 0.0061 ppsA; phosphoenolpyruvate synthase K01007; Psort location: Cytoplasmic, score: 8.96; Belongs to the RemA family.
  
    0.964
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.956
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 
 0.948
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
  
 
 0.939
EEU97193.1
Carboxylesterase; KEGG: ccr:CC0799 5.3e-62 para-nitrobenzyl esterase K03927; Belongs to the type-B carboxylesterase/lipase family.
    
 0.935
EEU97084.1
Carboxylesterase; KEGG: bja:bll4001 2.3e-53 putative esterase K03927; Belongs to the type-B carboxylesterase/lipase family.
    
 0.935
EEU96860.1
TIGR00255 family protein; Psort location: CytoplasmicMembrane, score: 9.82.
 
    0.932
EEU96537.1
KEGG: fnu:FN2073 7.8e-45 adenine phosphoribosyltransferase K00759; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.927
pyk
Pyruvate kinase; KEGG: tte:TTE1815 1.4e-159 pykF; pyruvate kinase K00873; Belongs to the pyruvate kinase family.
  
 
 0.899
Your Current Organism:
Faecalibacterium prausnitzii A2165
NCBI taxonomy Id: 411483
Other names: F. prausnitzii A2-165, Faecalibacterium prausnitzii A2-165
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.