STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.980
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.959
pflB
KEGG: bli:BL01863 4.8e-267 hypothetical formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.26.
    
 0.874
EEU96334.1
Hydrolase, alpha/beta domain protein; KEGG: zmo:ZMO0053 9.8e-15 pcaD; putative beta-ketoadipate enol-lactone hydrolase K01055; Psort location: Cytoplasmic, score: 8.96.
    
  0.757
EEU95682.1
Hypothetical protein.
    
  0.757
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.614
EEU95644.1
Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
 
  
 0.600
EEU96209.1
Class II glutamine amidotransferase; KEGG: bha:BH1728 4.2e-220 gltA; glutamate synthase (large subunit) K00265; Psort location: Cytoplasmic, score: 8.96; overlaps another CDS with the same product name.
     
 0.586
EEU96211.1
Hypothetical protein; KEGG: syn:sll1502 3.2e-213 gltB; NADH-dependent glutamate synthase large subunit K00268; Psort location: Cytoplasmic, score: 8.96; overlaps another CDS with the same product name.
     
 0.586
EEU96791.1
Hypothetical protein.
       0.572
Your Current Organism:
Faecalibacterium prausnitzii A2165
NCBI taxonomy Id: 411483
Other names: F. prausnitzii A2-165, Faecalibacterium prausnitzii A2-165
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.