STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiKEGG: cpf:CPF_2549 3.8e-139 pgi; glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.26; Belongs to the GPI family. (443 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; KEGG: tte:TTE1815 1.4e-159 pykF; pyruvate kinase K00873; Belongs to the pyruvate kinase family.
  
 
 0.999
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.995
pgk
Phosphoglycerate kinase; KEGG: cno:NT01CX_1411 2.9e-141 phosphoglycerate kinase K00927; Psort location: Cytoplasmic, score: 9.26.
  
 0.994
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.989
gap
KEGG: fth:FTH_1121 2.9e-118 gapA; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00134; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.980
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.979
pfp-2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.979
fba
Fructose-1,6-bisphosphate aldolase, class II; KEGG: cac:CAC0827 1.1e-109 fructose-bisphosphate aldolase K01624; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.978
pfkA
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
 0.978
nifJ
KEGG: cpr:CPR_2032 0. pyruvate-flavodoxin oxidoreductase K03737.
    
 0.965
Your Current Organism:
Faecalibacterium prausnitzii A2165
NCBI taxonomy Id: 411483
Other names: F. prausnitzii A2-165, Faecalibacterium prausnitzii A2-165
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.