STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hup-2DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (89 aa)    
Predicted Functional Partners:
EEU96564.1
S4 domain protein; KEGG: stc:str0522 4.6e-05 rluD; ribosomal large subunit pseudouridine synthase D K06180; Psort location: Cytoplasmic, score: 8.96.
  
    0.695
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.658
EEU96562.1
Hypothetical protein.
       0.642
EEU98353.1
Chorismate mutase; KEGG: bxe:Bxe_A0977 1.7e-42 bifunctional, chorismate mutase/prephenate dehydratase K01850; Psort location: Cytoplasmic, score: 9.97.
     
 0.589
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
  
 0.584
EEU96561.1
MazG nucleotide pyrophosphohydrolase domain protein; KEGG: pha:PSHAa0740 8.7e-11 mazG; nucleoside triphosphate pyrophosphohydrolase, non-specific K02428; Psort location: Cytoplasmic, score: 8.96.
       0.571
rplL
Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
  
  
 0.566
EEU96555.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.545
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
   0.542
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.528
Your Current Organism:
Faecalibacterium prausnitzii A2165
NCBI taxonomy Id: 411483
Other names: F. prausnitzii A2-165, Faecalibacterium prausnitzii A2-165
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.