STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemZKEGG: cpe:CPE1935 7.4e-88 hemZ; probable coproporphyrinogen III oxidase K02495; COG: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 9.98. (479 aa)    
Predicted Functional Partners:
EDR97645.1
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
0.843
EDR97716.1
Metallo-beta-lactamase domain protein; KEGG: ctc:CTC02196 1.8e-36 hydroxyacylglutathione hydrolase K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases; Psort location: Cytoplasmic, score: 8.87.
     
 0.843
hisS
histidine--tRNA ligase; KEGG: tte:TTE1230 2.6e-117 hisS; Histidyl-tRNA synthetase K01892; COG: COG0124 Histidyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00.
     
 0.821
EDR97718.1
HDIG domain protein; KEGG: ava:Ava_1777 8.1e-16 metal dependent phosphohydrolase, HD region with response regulator receiver modulation K07814; COG: COG2206 HD-GYP domain; Psort location: Cytoplasmic, score: 8.87.
       0.816
EDR97715.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.798
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.
 
  
 0.771
EDR97720.1
Hypothetical protein.
       0.741
argS
arginine--tRNA ligase; KEGG: cno:NT01CX_1587 1.8e-164 argS; arginyl-tRNA synthetase K01887; COG: COG0018 Arginyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.98.
  
    0.728
pyrB
KEGG: cac:CAC2654 4.8e-109 aspartate carbamoyltransferase catalytic subunit K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
       0.727
pyrI
Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: cac:CAC2653 1.0e-33 pyrI; aspartate carbamoyltransferase regulatory subunit K00610; COG: COG1781 Aspartate carbamoyltransferase, regulatory subunit; Psort location: Cytoplasmic, score: 8.87.
       0.727
Your Current Organism:
Anaerostipes caccae
NCBI taxonomy Id: 411490
Other names: A. caccae DSM 14662, Anaerostipes caccae DSM 14662
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.