STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR96085.1Glutamine amidotransferase, class I; KEGG: pca:Pcar_0731 9.4e-49 anthranilate synthase component II K01658; COG: COG0512 Anthranilate/para-aminobenzoate synthases component II; Psort location: Cytoplasmic, score: 8.87. (197 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 0.999
pabB
KEGG: fnu:FN1730 7.6e-118 para-aminobenzoate synthase component I / anthranilate synthase component I K01665; COG: COG0147 Anthranilate/para-aminobenzoate synthases component I; Psort location: Cytoplasmic, score: 8.87.
 0.999
trpC
KEGG: tte:TTE1580 3.9e-59 trpC; indole-3-glycerol phosphate synthase K01609; COG: COG0134 Indole-3-glycerol phosphate synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the TrpC family.
 
 0.998
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
0.984
EDR96083.1
Aminotransferase, class IV; KEGG: fnu:FN1729 1.2e-46 4-amino-4-deoxychorismate lyase K02619; COG: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; Psort location: Cytoplasmic, score: 10.00.
 
 
 0.980
EDR97038.1
AMP-binding enzyme; KEGG: bca:BCE_2400 1.4e-72 dhbE; 2,3-dihydroxybenzoate-AMP ligase K02312; COG: COG1021 Peptide arylation enzymes; Psort location: Cytoplasmic, score: 9.96.
  
 0.975
trpA-2
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 0.972
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 0.968
trpF
KEGG: tte:TTE1579 4.7e-47 trpF; phosphoribosylanthranilate isomerase K01817; COG: COG0135 Phosphoribosylanthranilate isomerase; Psort location: Cytoplasmic, score: 8.87; Belongs to the TrpF family.
 
 
 0.958
EDR98449.1
Chorismate mutase; KEGG: deh:cbdb_A424 7.4e-49 pheA; chorismate mutase/prephenate dehydratase (P-protein) K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.940
Your Current Organism:
Anaerostipes caccae
NCBI taxonomy Id: 411490
Other names: A. caccae DSM 14662, Anaerostipes caccae DSM 14662
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