Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BDU_137Uncharacterized conserved protein. (314 aa)    
Predicted Functional Partners:
BDU_407
Peptidyl-prolyl cis-trans isomerase; Probable lipoprotein (SpLip).
  
 0.904
greA
Transcription elongation factor EF; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
       0.866
rpsA
30S ribosomal protein S1.
  
   0.862
BDU_133
Pseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family.
   
   0.858
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
   0.857
BDU_130
Uncharacterized conserved protein.
       0.846
cmk
Cytidylate kinase.
       0.846
BDU_134
Uncharacterized conserved protein.
  
    0.846
BDU_138
Uncharacterized conserved protein.
  
   0.716
BDU_129
Uncharacterized conserved protein.
       0.712
Your Current Organism:
Borrelia duttonii
NCBI taxonomy Id: 412419
Other names: B. duttonii Ly, Borrelia duttonii Ly, Borrelia duttonii str. Ly, Borrelia duttonii strain Ly
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