STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Belongs to the MurCDEF family. (451 aa)    
Predicted Functional Partners:
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
 
 
 0.993
murC_1
UDP-N-acetylmuramate-alanine ligase (MurC); Cell wall formation; Belongs to the MurCDEF family.
 
 
 0.993
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
 
  
 0.983
murG
UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide); Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.981
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.972
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
  
 0.949
divIB
Cell division protein.
 
  
 0.947
murC_2
UDP-N-acetylmuramate-alanine ligase (MurC).
 
  
 0.938
ddlA
D-alanine--D-alanine ligase; Cell wall formation.
 
  
 0.895
ftsW
Cell division protein; Belongs to the SEDS family.
 
  
 0.848
Your Current Organism:
Borrelia duttonii
NCBI taxonomy Id: 412419
Other names: B. duttonii Ly, Borrelia duttonii Ly, Borrelia duttonii str. Ly, Borrelia duttonii strain Ly
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.