node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BDU_407 | rpsO | BDU_407 | BDU_812 | Peptidyl-prolyl cis-trans isomerase; Probable lipoprotein (SpLip). | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.873 |
BDU_407 | tgt | BDU_407 | BDU_817 | Peptidyl-prolyl cis-trans isomerase; Probable lipoprotein (SpLip). | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.700 |
BDU_407 | truB | BDU_407 | BDU_811 | Peptidyl-prolyl cis-trans isomerase; Probable lipoprotein (SpLip). | tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.516 |
BDU_814 | BDU_815 | BDU_814 | BDU_815 | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | Conserved hypothetical integral membrane protein; AKH motif (Prosite). | 0.818 |
BDU_814 | BDU_816 | BDU_814 | BDU_816 | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | Uncharacterized conserved protein. | 0.818 |
BDU_814 | BDU_819 | BDU_814 | BDU_819 | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | Uncharacterized conserved protein. | 0.778 |
BDU_814 | mviN | BDU_814 | BDU_818 | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | Virulence factor MviN protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.778 |
BDU_814 | pnpA | BDU_814 | BDU_813 | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.809 |
BDU_814 | rpsO | BDU_814 | BDU_812 | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.785 |
BDU_814 | tgt | BDU_814 | BDU_817 | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.778 |
BDU_814 | truB | BDU_814 | BDU_811 | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.494 |
BDU_815 | BDU_814 | BDU_815 | BDU_814 | Conserved hypothetical integral membrane protein; AKH motif (Prosite). | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | 0.818 |
BDU_815 | BDU_816 | BDU_815 | BDU_816 | Conserved hypothetical integral membrane protein; AKH motif (Prosite). | Uncharacterized conserved protein. | 0.990 |
BDU_815 | BDU_819 | BDU_815 | BDU_819 | Conserved hypothetical integral membrane protein; AKH motif (Prosite). | Uncharacterized conserved protein. | 0.778 |
BDU_815 | mviN | BDU_815 | BDU_818 | Conserved hypothetical integral membrane protein; AKH motif (Prosite). | Virulence factor MviN protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.782 |
BDU_815 | pnpA | BDU_815 | BDU_813 | Conserved hypothetical integral membrane protein; AKH motif (Prosite). | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.809 |
BDU_815 | rpsO | BDU_815 | BDU_812 | Conserved hypothetical integral membrane protein; AKH motif (Prosite). | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.785 |
BDU_815 | tgt | BDU_815 | BDU_817 | Conserved hypothetical integral membrane protein; AKH motif (Prosite). | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.801 |
BDU_815 | truB | BDU_815 | BDU_811 | Conserved hypothetical integral membrane protein; AKH motif (Prosite). | tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.505 |
BDU_816 | BDU_814 | BDU_816 | BDU_814 | Uncharacterized conserved protein. | Uncharacterized conserved protein; Probable lipoprotein (SpLip). | 0.818 |