node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDR76180.1 | SDR76472.1 | SAMN04489834_0167 | SAMN04489834_0176 | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.963 |
SDR76180.1 | SDR76531.1 | SAMN04489834_0167 | SAMN04489834_0177 | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.984 |
SDR76180.1 | SDR76601.1 | SAMN04489834_0167 | SAMN04489834_0179 | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | Chlorite dismutase. | 0.503 |
SDR76180.1 | SDR76730.1 | SAMN04489834_0167 | SAMN04489834_0183 | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | Oxygen-dependent protoporphyrinogen oxidase. | 0.710 |
SDR76180.1 | hemA | SAMN04489834_0167 | SAMN04489834_0185 | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.954 |
SDR76180.1 | hemE | SAMN04489834_0167 | SAMN04489834_0184 | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.884 |
SDR76180.1 | hemH | SAMN04489834_0167 | SAMN04489834_0178 | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.492 |
SDR76180.1 | hemH-2 | SAMN04489834_0167 | SAMN04489834_1563 | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.426 |
SDR76180.1 | hemL | SAMN04489834_0167 | SAMN04489834_0166 | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.995 |
SDR76472.1 | SDR76180.1 | SAMN04489834_0176 | SAMN04489834_0167 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | 0.963 |
SDR76472.1 | SDR76531.1 | SAMN04489834_0176 | SAMN04489834_0177 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.993 |
SDR76472.1 | SDR76601.1 | SAMN04489834_0176 | SAMN04489834_0179 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Chlorite dismutase. | 0.865 |
SDR76472.1 | SDR76730.1 | SAMN04489834_0176 | SAMN04489834_0183 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Oxygen-dependent protoporphyrinogen oxidase. | 0.675 |
SDR76472.1 | hemA | SAMN04489834_0176 | SAMN04489834_0185 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.857 |
SDR76472.1 | hemE | SAMN04489834_0176 | SAMN04489834_0184 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.671 |
SDR76472.1 | hemH | SAMN04489834_0176 | SAMN04489834_0178 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.863 |
SDR76472.1 | hemH-2 | SAMN04489834_0176 | SAMN04489834_1563 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.417 |
SDR76472.1 | hemL | SAMN04489834_0176 | SAMN04489834_0166 | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Glutamate-1-semialdehyde 2,1-aminomutase. | 0.750 |
SDR76531.1 | SDR76180.1 | SAMN04489834_0177 | SAMN04489834_0167 | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Porphobilinogen synthase; Non-canonical start codon; manually curated; Belongs to the ALAD family. | 0.984 |
SDR76531.1 | SDR76472.1 | SAMN04489834_0177 | SAMN04489834_0176 | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen III methyltransferase / synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.993 |