STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDR80689.1L-threonine ammonia-lyase. (310 aa)    
Predicted Functional Partners:
SDS44283.1
Acetolactate synthase, small subunit.
  
 
 0.870
ilvD
Dihydroxyacid dehydratase; Manually curated; Belongs to the IlvD/Edd family.
 
  
 0.782
SDS44234.1
Acetolactate synthase, large subunit.
  
 0.741
SDS67943.1
Glutamate synthase (NADH) large subunit.
  
 
 0.741
SDT31771.1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
  
 0.737
SDS35178.1
L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.732
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.674
SDS00529.1
2-iminobutanoate/2-iminopropanoate deaminase.
 
 
 0.562
SDS35134.1
Homoserine dehydrogenase.
  
  
 0.551
SDS48483.1
Branched chain amino acid aminotransferase apoenzyme.
  
  
 0.550
Your Current Organism:
Microterricola viridarii
NCBI taxonomy Id: 412690
Other names: DSM 21772, JCM 15926, M. viridarii, Microterricola viridarii Matsumoto et al. 2008, NBRC 102123, NRRL B-24538, actinobacterium KV-677, strain KV-677
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