node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDR79485.1 | SDS52348.1 | SAMN04489834_0256 | SAMN04489834_1639 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.947 |
SDR79485.1 | SDS91696.1 | SAMN04489834_0256 | SAMN04489834_2431 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase-1. | 0.404 |
SDR79485.1 | acpP | SAMN04489834_0256 | SAMN04489834_2174 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.519 |
SDR79485.1 | polA | SAMN04489834_0256 | SAMN04489834_1934 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
SDR79485.1 | thyA | SAMN04489834_0256 | SAMN04489834_2680 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.781 |
SDS52277.1 | SDS52348.1 | SAMN04489834_1638 | SAMN04489834_1639 | Signal peptidase I; Belongs to the peptidase S26 family. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.946 |
SDS52277.1 | SDS52399.1 | SAMN04489834_1638 | SAMN04489834_1640 | Signal peptidase I; Belongs to the peptidase S26 family. | Protein of unknown function. | 0.746 |
SDS52277.1 | rplS | SAMN04489834_1638 | SAMN04489834_1637 | Signal peptidase I; Belongs to the peptidase S26 family. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.716 |
SDS52277.1 | trmD | SAMN04489834_1638 | SAMN04489834_1634 | Signal peptidase I; Belongs to the peptidase S26 family. | tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.405 |
SDS52348.1 | SDR79485.1 | SAMN04489834_1639 | SAMN04489834_0256 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.947 |
SDS52348.1 | SDS52277.1 | SAMN04489834_1639 | SAMN04489834_1638 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.946 |
SDS52348.1 | SDS52399.1 | SAMN04489834_1639 | SAMN04489834_1640 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Protein of unknown function. | 0.771 |
SDS52348.1 | SDS91696.1 | SAMN04489834_1639 | SAMN04489834_2431 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA topoisomerase-1. | 0.760 |
SDS52348.1 | acpP | SAMN04489834_1639 | SAMN04489834_2174 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.692 |
SDS52348.1 | polA | SAMN04489834_1639 | SAMN04489834_1934 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.802 |
SDS52348.1 | rnhA | SAMN04489834_1639 | SAMN04489834_3520 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.793 |
SDS52348.1 | rplS | SAMN04489834_1639 | SAMN04489834_1637 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.775 |
SDS52348.1 | thyA | SAMN04489834_1639 | SAMN04489834_2680 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.708 |
SDS52348.1 | trmD | SAMN04489834_1639 | SAMN04489834_1634 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.682 |
SDS52399.1 | SDS52277.1 | SAMN04489834_1640 | SAMN04489834_1638 | Protein of unknown function. | Signal peptidase I; Belongs to the peptidase S26 family. | 0.746 |