node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDS76798.1 | SDS76835.1 | SAMN04489834_2109 | SAMN04489834_2110 | Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily. | DNA gyrase subunit A. | 0.709 |
SDS76835.1 | SDS76798.1 | SAMN04489834_2110 | SAMN04489834_2109 | DNA gyrase subunit A. | Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily. | 0.709 |
SDS76835.1 | SDS76998.1 | SAMN04489834_2110 | SAMN04489834_2113 | DNA gyrase subunit A. | DNA topoisomerase IV subunit B. | 0.989 |
SDS76835.1 | dnaJ | SAMN04489834_2110 | SAMN04489834_2330 | DNA gyrase subunit A. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.570 |
SDS76835.1 | dnaK | SAMN04489834_2110 | SAMN04489834_0374 | DNA gyrase subunit A. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.752 |
SDS76835.1 | ftsZ | SAMN04489834_2110 | SAMN04489834_2378 | DNA gyrase subunit A. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.619 |
SDS76835.1 | gyrB | SAMN04489834_2110 | SAMN04489834_0252 | DNA gyrase subunit A. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.998 |
SDS76835.1 | pheT | SAMN04489834_2110 | SAMN04489834_2641 | DNA gyrase subunit A. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.666 |
SDS76835.1 | rpoA | SAMN04489834_2110 | SAMN04489834_1008 | DNA gyrase subunit A. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.609 |
SDS76835.1 | rpoC | SAMN04489834_2110 | SAMN04489834_0947 | DNA gyrase subunit A. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.579 |
SDS76835.1 | tuf | SAMN04489834_2110 | SAMN04489834_0975 | DNA gyrase subunit A. | Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.588 |
SDS76998.1 | SDS76835.1 | SAMN04489834_2113 | SAMN04489834_2110 | DNA topoisomerase IV subunit B. | DNA gyrase subunit A. | 0.989 |
SDS76998.1 | dnaJ | SAMN04489834_2113 | SAMN04489834_2330 | DNA topoisomerase IV subunit B. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.566 |
SDS76998.1 | dnaK | SAMN04489834_2113 | SAMN04489834_0374 | DNA topoisomerase IV subunit B. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.860 |
SDS76998.1 | ftsZ | SAMN04489834_2113 | SAMN04489834_2378 | DNA topoisomerase IV subunit B. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.520 |
SDS76998.1 | pheT | SAMN04489834_2113 | SAMN04489834_2641 | DNA topoisomerase IV subunit B. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.660 |
SDS76998.1 | rpoA | SAMN04489834_2113 | SAMN04489834_1008 | DNA topoisomerase IV subunit B. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.444 |
SDS76998.1 | rpoC | SAMN04489834_2113 | SAMN04489834_0947 | DNA topoisomerase IV subunit B. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.438 |
dnaJ | SDS76835.1 | SAMN04489834_2330 | SAMN04489834_2110 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | DNA gyrase subunit A. | 0.570 |
dnaJ | SDS76998.1 | SAMN04489834_2330 | SAMN04489834_2113 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | DNA topoisomerase IV subunit B. | 0.566 |