node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COSY_0073 | folE2 | COSY_0073 | COSY_0286 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.807 |
COSY_0073 | moaA | COSY_0073 | COSY_0643 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.800 |
COSY_0073 | ndk | COSY_0073 | COSY_0355 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.903 |
COSY_0073 | ribAB | COSY_0073 | COSY_0463 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Bifunctional riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.800 |
COSY_0073 | spoT | COSY_0073 | COSY_0471 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.914 |
folE2 | COSY_0073 | COSY_0286 | COSY_0073 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.807 |
folE2 | moaA | COSY_0286 | COSY_0643 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.900 |
folE2 | ndk | COSY_0286 | COSY_0355 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.800 |
folE2 | ribAB | COSY_0286 | COSY_0463 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Bifunctional riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.902 |
folE2 | spoT | COSY_0286 | COSY_0471 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.800 |
moaA | COSY_0073 | COSY_0643 | COSY_0073 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.800 |
moaA | folE2 | COSY_0643 | COSY_0286 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.900 |
moaA | moaC | COSY_0643 | COSY_0642 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.999 |
moaA | moaD | COSY_0643 | COSY_0644 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdenum cofactor biosynthesis protein D. | 0.908 |
moaA | moaE | COSY_0643 | COSY_0639 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdenum cofactor biosynthesis protein E; Molybdopterin converting factor, subunit 2. | 0.847 |
moaA | mobA | COSY_0643 | COSY_0640 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. | 0.791 |
moaA | moeA | COSY_0643 | COSY_0641 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.986 |
moaA | ndk | COSY_0643 | COSY_0355 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.800 |
moaA | ribAB | COSY_0643 | COSY_0463 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Bifunctional riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.900 |
moaA | spoT | COSY_0643 | COSY_0471 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.800 |