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hemL protein (Ruthia magnifica) - STRING interaction network
"hemL" - TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase in Ruthia magnifica
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hemLTIGRFAM- glutamate-1-semialdehyde-2,1-aminomutase; PFAM- aminotransferase class-III; KEGG- cps-CPS_4629 glutamate-1-semialdehyde-2,1-aminomutase (428 aa)    
Predicted Functional Partners:
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA); Belongs to the glutamyl-tRNA reductase family (416 aa)
 
  0.994
Rmag_0409
PFAM- delta-aminolevulinic acid dehydratase; KEGG- tcx-Tcr_0154 porphobilinogen synthase; Belongs to the ALAD family (328 aa)
 
 
  0.990
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family (304 aa)
 
   
  0.886
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (472 aa)
 
  0.861
thiE
Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP); Belongs to the thiamine-phosphate synthase family (193 aa)
 
   
  0.791
Rmag_0607
PFAM- alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG- csa-Csal_2817 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen (149 aa)
 
        0.772
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (146 aa)
            0.763
Rmag_0853
PFAM- Uroporphyrinogen III synthase HEM4; KEGG- mca-MCA3061 uroporphyrinogen-III synthase/uroporphyrin-III C-methyltransferase (248 aa)
   
 
  0.735
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (347 aa)
 
   
  0.722
Rmag_0221
KEGG- cbu-CBU_0500 DNA polymerase III, delta prime subunit; similar to ATPases involved in DNA replication (335 aa)
              0.717
Your Current Organism:
Ruthia magnifica
NCBI taxonomy Id: 413404
Other names: C. Ruthia magnifica str. Cm (Calyptogena magnifica), Candidatus Ruthia magnifica str. Cm (Calyptogena magnifica), Candidatus Ruthia magnifica strain Cm (Calyptogena magnifica), Ruthia magnifica, Ruthia magnifica str. Cm (Calyptogena magnifica)
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