| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rmag_0560 | clpP | Rmag_0560 | Rmag_0205 | TIGRFAM: RNA polymerase sigma factor RpoH; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: ilo:IL0229 DNA-directed RNA polymerase sigma 32 subunit. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.421 |
| Rmag_0560 | dnaJ | Rmag_0560 | Rmag_0352 | TIGRFAM: RNA polymerase sigma factor RpoH; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: ilo:IL0229 DNA-directed RNA polymerase sigma 32 subunit. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.693 |
| Rmag_0560 | dnaK | Rmag_0560 | Rmag_0353 | TIGRFAM: RNA polymerase sigma factor RpoH; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: ilo:IL0229 DNA-directed RNA polymerase sigma 32 subunit. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.413 |
| Rmag_0560 | groL | Rmag_0560 | Rmag_0562 | TIGRFAM: RNA polymerase sigma factor RpoH; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: ilo:IL0229 DNA-directed RNA polymerase sigma 32 subunit. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.864 |
| Rmag_0560 | groS | Rmag_0560 | Rmag_0561 | TIGRFAM: RNA polymerase sigma factor RpoH; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: ilo:IL0229 DNA-directed RNA polymerase sigma 32 subunit. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.757 |
| Rmag_0560 | grpE | Rmag_0560 | Rmag_1055 | TIGRFAM: RNA polymerase sigma factor RpoH; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: ilo:IL0229 DNA-directed RNA polymerase sigma 32 subunit. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.492 |
| Rmag_0560 | hscA | Rmag_0560 | Rmag_0573 | TIGRFAM: RNA polymerase sigma factor RpoH; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: ilo:IL0229 DNA-directed RNA polymerase sigma 32 subunit. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.413 |
| acpP | dnaJ | Rmag_0565 | Rmag_0352 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.960 |
| acpP | groL | Rmag_0565 | Rmag_0562 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.439 |
| acpP | groS | Rmag_0565 | Rmag_0561 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.617 |
| acpP | rplL | Rmag_0565 | Rmag_0812 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.848 |
| clpP | Rmag_0560 | Rmag_0205 | Rmag_0560 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | TIGRFAM: RNA polymerase sigma factor RpoH; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: ilo:IL0229 DNA-directed RNA polymerase sigma 32 subunit. | 0.421 |
| clpP | dnaJ | Rmag_0205 | Rmag_0352 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.588 |
| clpP | dnaK | Rmag_0205 | Rmag_0353 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.579 |
| clpP | groL | Rmag_0205 | Rmag_0562 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.656 |
| clpP | groS | Rmag_0205 | Rmag_0561 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.640 |
| clpP | grpE | Rmag_0205 | Rmag_1055 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.673 |
| clpP | hscA | Rmag_0205 | Rmag_0573 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.579 |
| clpP | htpG | Rmag_0205 | Rmag_0493 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.509 |
| clpP | rplL | Rmag_0205 | Rmag_0812 | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | LSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.538 |
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