STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (348 aa)    
Predicted Functional Partners:
trpG
Anthranilate synthase component II.
 
 0.999
AAW51_3386
Para-aminobenzoate synthase, amidotransferase component.
 0.999
trpG-2
Anthranilate synthase component II.
 
 0.999
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 0.999
trpF
N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
 
 
 0.997
trpC
Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
  
 0.997
AAW51_3387
Para-aminobenzoate synthase, amidotransferase component.
 
 
 0.994
pabBC-2
Para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase.
 
 
 0.985
pabBC
Aminobenzoate synthetase.
 
 
 0.984
trpB
Tryptophan synthase subunit alpha; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.973
Your Current Organism:
Polyangium brachysporum
NCBI taxonomy Id: 413882
Other names: ATCC 53080, DSM 7029, NBRC 100090, [. brachysporum, [Polyangium] brachysporum, strain K481-B101
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