STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO0053Similar to Bacillus subtilis lysine decarboxylase Cad or bsu14630 SWALL:DCLY_BACSU (SWALL:P21885) (490 aa) fasta scores: E(): 1.9e-43, 31.13 38d in 485 aa, and to Clostridium acetobutylicum lysine decarboxylase cac0297 SWALL:Q97MA1 (EMBL:AE007544) (481 aa) fasta scores: E(): 7.2e-94, 53.95 38d in 480 aa. (482 aa)    
Predicted Functional Partners:
CBO0052A
Conserved hypothetical protein.
       0.873
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
    0.870
CBO0055
Conserved hypothetical protein; Similar to Clostridium acetobutylicum protein from nitrogen regulatory protein P-II cac0299 SWALL:Q97M99 (EMBL:AE007544) (109 aa) fasta scores: E(): 4.1e-29,76.14 38d in 109 aa, and to Clostridium perfringens hypothetical protein Cpe2450 SWALL:Q8XHN3 (EMBL:AP003194) (109 aa) fasta scores: E(): 7.9e-23, 60.55 38d in 109 aa.
  
    0.739
CBO1796
Conserved hypothetical protein.
 
   
 0.731
CBO0057
Putative signal peptidase II; Similar to Treponema pallidum Tpl protein or tp0046 SWALL:TPL_TREPA (SWALL:P45685) (233 aa) fasta scores: E(): 5.7e-21, 37.68 38d in 207 aa, and to Clostridium tetani Tpl protein ctc00222 SWALL:Q899F7 (EMBL:AE015936) (302 aa) fasta scores: E(): 6.2e-79, 72.36 38d in 304 aa.
  
    0.718
CBO0056
Similar to Escherichia coli DNA polymerase III,delta' subunit HolB or b1099 SWALL:HOLB_ECOLI (SWALL:P28631) (334 aa) fasta scores: E(): 1.3e-05, 22.05 id in 263 aa, and to Clostridium tetani DNA polymerase III delta subunit ctc00221 SWALL:Q899F8 (EMBL:AE015936) (322 aa) fasta scores: E(): 1.1e-52, 53.35 38d in 313 aa.
       0.705
CBO0058
Putative metal-binding protein; Similar to Pseudomonas sp periplasmic mercuric ion binding protein MerP SWALL:Q936U4 (EMBL:Y18360) (92 aa) fasta scores: E(): 0.64, 36.95 38d in 46 aa, and to Clostridium acetobutylicum predicted metal-binding protein of ferredoxin fold cac0302 SWALL:Q97M96 (EMBL:AE007544) (67 aa) fasta scores: E(): 7.5e-09, 43.28 38d in 67 aa.
       0.698
CBO0052
Putative amidohydrolase; Similar to Staphylococcus aureus HmrA or mw2057 SWALL:Q8NVF8 (EMBL:AP004829) (394 aa) fasta scores: E(): 4.7e-30, 28.68 38d in 387 aa, and to Clostridium tetani amidohydrolase ctc00218 SWALL:Q899G1 (EMBL:AE015936) (392 aa) fasta scores: E(): 1.3e-71, 50.39 38d in 383 aa, and to Escherichia coli aminobenzoyl-glutamate utilization protein b abgb or b1337 SWALL:ABGB_ECOLI (SWALL:P76052) (481 aa) fasta scores: E(): 0.0002, 25.46 38d in 326 aa; Belongs to the peptidase M20A family.
       0.691
fer
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
 
     0.620
CBO3064
Putative radical SAM protein; Partially similar to Escherichia coli putative arylsulfatase regulatory protein AslB or AtsB or b3800 SWALL:ASLB_ECOLI (SWALL:P25550) (411 aa) fasta scores: E(): 0.02, 24.22 38d in 355 aa.
 
     0.482
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (26%) [HD]