Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBO0072Putative Na+ driven multidrug efflux pump; Similar to Vibrio parahaemolyticus multidrug resistance protein NorM or vp1479 SWALL:NORM_VIBPA (SWALL:O82855) (456 aa) fasta scores: E(): 8.1e-23, 26.57 id in 414 aa, and to Clostridium tetani Na+ driven multidrug efflux pump ctc01799 SWALL:Q893L8 (EMBL:AE015942) (455 aa) fasta scores: E(): 6.5e-93,52.71 38d in 442 aa. (445 aa)    
Predicted Functional Partners:
CBO0073
Putative uracil-DNA glycosylase; Similar to Clostridium tetani DNA polymerase,bacteriophage-type ctc00242 SWALL:Q899E0 (EMBL:AE015936) (188 aa) fasta scores: E(): 1e-52, 63.97 38d in 186 aa,and to Thermoanaerobacter tengcongensis uracil-DNA glycosylase tte0077 SWALL:Q8RDF7 (EMBL:AE012981) (186 aa) fasta scores: E(): 4.2e-42, 56.21 38d in 185 aa.
       0.560
CBO0364
Putative phosphatase; Similar to Clostridium tetani ser/thr and tyr protein phosphatase ctc02044 SWALL:Q892P9 (EMBL:AE015943) (208 aa) fasta scores: E(): 6e-36, 43.35 38d in 203 aa.
   
    0.521
CBO0074
MarR-family transcriptional regulator; Similar to Bacillus subtilis organic hydroperoxide resistance transcriptional regulator OhrR or bsu13150 SWALL:OHRR_BACSU (SWALL:O34777) (147 aa) fasta scores: E(): 0.00012, 27.27 38d in 143 aa, and to Staphylococcus aureus hypothetical protein sav2386 or sa2174 SWALL:Q99RP3 (EMBL:AP003365) (148 aa) fasta scores: E(): 1.4e-05,28.87 38d in 142 aa.
  
    0.490
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
  
 0.481
gap1
Similar to Bacillus megaterium glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_BACME (SWALL:P23722) (334 aa) fasta scores: E(): 4.3e-78, 64.86 id in 333 aa, and to Bacillus stearothermophilus glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_BACST (SWALL:P00362) (334 aa) fasta scores: E(): 4.1e-82, 69.06 38d in 333 aa; Also similar to CBO1095 (66.26 38d).
   
    0.456
gapA2
Glyceraldehyde 3-phosphate dehydrogenase A; Also similar to CBO0226 (66.26 38d); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
    0.456
CBO2127
Putative transmembrane MATE family transporter protein.
  
     0.418
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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