Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0074MarR-family transcriptional regulator; Similar to Bacillus subtilis organic hydroperoxide resistance transcriptional regulator OhrR or bsu13150 SWALL:OHRR_BACSU (SWALL:O34777) (147 aa) fasta scores: E(): 0.00012, 27.27 38d in 143 aa, and to Staphylococcus aureus hypothetical protein sav2386 or sa2174 SWALL:Q99RP3 (EMBL:AP003365) (148 aa) fasta scores: E(): 1.4e-05,28.87 38d in 142 aa. (144 aa)    
Predicted Functional Partners:
CBO0073
Putative uracil-DNA glycosylase; Similar to Clostridium tetani DNA polymerase,bacteriophage-type ctc00242 SWALL:Q899E0 (EMBL:AE015936) (188 aa) fasta scores: E(): 1e-52, 63.97 38d in 186 aa,and to Thermoanaerobacter tengcongensis uracil-DNA glycosylase tte0077 SWALL:Q8RDF7 (EMBL:AE012981) (186 aa) fasta scores: E(): 4.2e-42, 56.21 38d in 185 aa.
       0.693
opuCB
Glycine betaine/carnitine/choline transport system permease protein opucb.
  
  
 0.503
CBO0183
Putative pyridine nucleotide-disulphide oxidoreductase; Similar to Fusobacterium nucleatum coenzyme a disulfide reductase/ disulfide bond regulator domain fn1903 SWALL:Q8RHU1 (EMBL:AE010492) (810 aa) fasta scores: E(): 1e-163, 56.35 38d in 818 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 coenzyme a disulfide reductase/ disulfide bond regulator domain fnv2089 SWALL:Q7P7P1 (EMBL:AABF01000012) (809 aa) fasta scores: E(): 2.7e-159, 55.5 38d in 818 aa; Belongs to the sulfur carrier protein TusA family.
  
  
 0.499
CBO0072
Putative Na+ driven multidrug efflux pump; Similar to Vibrio parahaemolyticus multidrug resistance protein NorM or vp1479 SWALL:NORM_VIBPA (SWALL:O82855) (456 aa) fasta scores: E(): 8.1e-23, 26.57 id in 414 aa, and to Clostridium tetani Na+ driven multidrug efflux pump ctc01799 SWALL:Q893L8 (EMBL:AE015942) (455 aa) fasta scores: E(): 6.5e-93,52.71 38d in 442 aa.
  
    0.490
CBO3250
Putative ABC transporter, permease protein; 5 probable transmembrane helices predicted for CBO3249 by TMHMM2.0 at aa 28-46, 89-106, 119-138, 143-162 and 183-205.
  
     0.432
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
       0.402
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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