Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0105Conserved hypothetical protein; Similar to Myxococcus xanthus phosphoribosyl amino imidizole carboxylase-like protein SWALL:Q8VQZ2 (EMBL:AF449411) (250 aa) fasta scores: E(): 2.7e-43,52.43 38d in 246 aa, and to Clostridium acetobutylicum ncair mutase cac0776 SWALL:Q97KZ0 (EMBL:AE007592) (248 aa) fasta scores: E(): 4.2e-63, 71.37 38d in 248 aa. (248 aa)    
Predicted Functional Partners:
larC
Conserved hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.984
CBO0104
Conserved hypothetical protein; Similar to Clostridium acetobutylicum ATP-utilizing enzyme of the pp-loop superfamily cac0775 SWALL:Q97KZ1 (EMBL:AE007592) (271 aa) fasta scores: E(): 9.6e-58,59.62 38d in 265 aa, and to Thermoanaerobacter tengcongensis ATP-utilizing enzymes of the pp-loop superfamily tte0769 SWALL:Q8RBP5 (EMBL:AE013044) (255 aa) fasta scores: E(): 7.3e-44, 54.09 38d in 244 aa.
 
  
 0.978
CBO1183
Conserved hypothetical protein.
 
  
 0.928
CBO1006
Conserved hypothetical protein.
 
  
 0.849
CBO2019
Conserved hypothetical protein.
 
  
 0.823
CBO1814
Conserved hypothetical protein.
 
  
 0.821
cbiM
Putative cobalt transport protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.673
CBO0106
Radical SAM superfamily protein; Similar to Clostridium tetani Fe-s oxidoreductase ctc00266 SWALL:Q899B9 (EMBL:AE015936) (460 aa) fasta scores: E(): 2.1e-137, 71.08 38d in 460 aa, and to Clostridium acetobutylicum moaa/nirj family fe-s oxidoreductase cac2791 SWALL:Q97FE9 (EMBL:AE007776) (461 aa) fasta scores: E(): 2.8e-119, 61.6 38d in 461 aa.
       0.465
cinA
Putative molybdopterin binding; Similar to Bacillus subtilis cina-like protein CinA or bsu16930 SWALL:CINA_BACSU (SWALL:P46323) (416 aa) fasta scores: E(): 6.2e-57, 44.92 38d in 394 aa, and to Clostridium acetobutylicum competence-damage inducible protein, cina cac3586 SWALL:Q97D94 (EMBL:AE007855) (411 aa) fasta scores: E(): 1.3e-92, 60.29 38d in 408 aa; Belongs to the CinA family.
       0.410
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
       0.410
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.