STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0106Radical SAM superfamily protein; Similar to Clostridium tetani Fe-s oxidoreductase ctc00266 SWALL:Q899B9 (EMBL:AE015936) (460 aa) fasta scores: E(): 2.1e-137, 71.08 38d in 460 aa, and to Clostridium acetobutylicum moaa/nirj family fe-s oxidoreductase cac2791 SWALL:Q97FE9 (EMBL:AE007776) (461 aa) fasta scores: E(): 2.8e-119, 61.6 38d in 461 aa. (460 aa)    
Predicted Functional Partners:
CBO0107
Solute-binding protein; Similar to Agrobacterium radiobacter lactose-binding protein precursor LacE SWALL:LACE_AGRRD (SWALL:P29822) (422 aa) fasta scores: E(): 1.9e-12, 21.24 id in 386 aa, and to Clostridium acetobutylicum sugar-binding periplasmic protein cac2912 SWALL:Q97F41 (EMBL:AE007788) (432 aa) fasta scores: E(): 4.3e-18,22.63 38d in 433 aa.
       0.555
CBO3192
Putative ferredoxin.
  
     0.479
CBO0105
Conserved hypothetical protein; Similar to Myxococcus xanthus phosphoribosyl amino imidizole carboxylase-like protein SWALL:Q8VQZ2 (EMBL:AF449411) (250 aa) fasta scores: E(): 2.7e-43,52.43 38d in 246 aa, and to Clostridium acetobutylicum ncair mutase cac0776 SWALL:Q97KZ0 (EMBL:AE007592) (248 aa) fasta scores: E(): 4.2e-63, 71.37 38d in 248 aa.
       0.465
larC
Conserved hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
       0.426
CBO0104
Conserved hypothetical protein; Similar to Clostridium acetobutylicum ATP-utilizing enzyme of the pp-loop superfamily cac0775 SWALL:Q97KZ1 (EMBL:AE007592) (271 aa) fasta scores: E(): 9.6e-58,59.62 38d in 265 aa, and to Thermoanaerobacter tengcongensis ATP-utilizing enzymes of the pp-loop superfamily tte0769 SWALL:Q8RBP5 (EMBL:AE013044) (255 aa) fasta scores: E(): 7.3e-44, 54.09 38d in 244 aa.
       0.411
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.