STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CBO0127Putative cell wall synthesis protein; Similar to Clostridium tetani 1,2-diacylglycerol 3-glucosyltransferase ctc00289 SWALL:Q898Z7 (EMBL:AE015936) (389 aa) fasta scores: E(): 1.7e-81,59.38 38d in 389 aa, and to Clostridium acetobutylicum predicted udp-glucuronosyltransferase, ypfp b/subtilis ortholog cac2897 SWALL:Q97F56 (EMBL:AE007787) (384 aa) fasta scores: E(): 4.3e-80, 59.53 38d in 383 aa. (413 aa)    
Predicted Functional Partners:
CBO0593
Putative sulfatase.
  
 
 0.919
CBO2861
Putative sulfatase.
  
 
 0.919
CBO2948
N-terminal region similar to diacylglycerol kinase,and C-terminal region to phosphatases.
  
 
  0.908
lipA
Putative secreted lipase.
     
  0.900
CBO2061
Putative secreted lipase.
     
  0.900
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.887
cphA
Similar to Anabaena variabilis cyanophycin synthetase CphA SWALL:CPHA_ANAVA (SWALL:O86109) (901 aa) fasta scores: E(): 5.5e-116, 39.86 38d in 868 aa, and to Clostridium tetani cyanophycin synthetase ctc00282 SWALL:Q899A3 (EMBL:AE015936) (874 aa) fasta scores: E(): 3e-189, 57.98 38d in 864 aa.
  
 
 0.856
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.824
divIB
Cell division protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
  
  
 0.798
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.767
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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