STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0137Uputative membrane protein; Similar to Clostridium acetobutylicum uncharacterized conserved protein, predicted metal-dependent enzyme, yqhq b.subtilis ortholog cac2886 SWALL:Q97F66 (EMBL:AE007786) (317 aa) fasta scores: E(): 6.8e-73, 60.39 38d in 308 aa, and to Clostridium tetani conserved protein ctc00300 SWALL:Q898Y7 (EMBL:AE015936) (249 aa) fasta scores: E(): 2.2e-65, 67.33 38d in 248 aa. (305 aa)    
Predicted Functional Partners:
prmC
Protein methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
     0.981
tdK
Thymidine kinase; Similar to Rhodothermus sp. thymidine kinase Tdk SWALL:KITH_RHOSI (SWALL:Q9ZIG2) (213 aa) fasta scores: E(): 2.6e-34, 53.26 38d in 184 aa, and to Clostridium acetobutylicum thymidine kinase cac2887 SWALL:Q97F65 (EMBL:AE007786) (195 aa) fasta scores: E(): 5.1e-56,77.48 38d in 191 aa.
  
    0.821
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.701
CBO0140
Putative membrane protein; Similar to Clostridium tetani hypothetical membrane protein ctc00303 SWALL:Q898Y4 (EMBL:AE015936) (200 aa) fasta scores: E(): 1.4e-28, 46.19 38d in 197 aa, and to Clostridium acetobutylicum predicted membrane protein cac2883 SWALL:Q97F69 (EMBL:AE007785) (192 aa) fasta scores: E(): 1.2e-26, 40.1 38d in 197 aa.
       0.615
rpmE
50S ribosomal protein L31; Binds the 23S rRNA.
       0.583
CBO0141
Putative zinc transporter; Similar to Escherichia coli, Escherichia coli O6,and Escherichia coli O157:H7 zinc transporter ZupTt or b3040 or c3789 or z4397 or ecs3928 SWALL:ZUPT_ECOLI (SWALL:P24198) (257 aa) fasta scores: E(): 3.9e-08, 27.53 id in 247 aa, and to Clostridium tetani zinc uptake transporter ctc00304 SWALL:Q898Y3 (EMBL:AE015936) (236 aa) fasta scores: E(): 8.5e-49, 53.81 38d in 236 aa.
       0.538
CBO0142
Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
       0.519
CBO0143
Similar to Acinetobacter johnsonii low molecular weight protein-tyrosine-phosphatase Ptp SWALL:PTP_ACIJO (SWALL:O52787) (142 aa) fasta scores: E(): 4.2e-06, 33.59 id in 128 aa, and to Clostridium tetani phosphotyrosine protein phosphatase ctc00306 SWALL:Q898Y1 (EMBL:AE015936) (154 aa) fasta scores: E(): 1.9e-24, 54.05 38d in 148 aa.
       0.514
rpiB
Similar to Escherichia coli ribose 5-phosphate isomerase B RpiB or b4090 SWALL:RPIB_ECOLI (SWALL:P37351) (149 aa) fasta scores: E(): 2.2e-27, 52.77 38d in 144 aa,and to Clostridium tetani ribose 5-phosphate isomerase ctc00307 SWALL:Q898Y0 (EMBL:AE015936) (149 aa) fasta scores: E(): 1.5e-43, 78.47 38d in 144 aa.
       0.469
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
       0.449
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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