Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prmCProtein methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (283 aa)    
Predicted Functional Partners:
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
 
 
 0.996
CBO0137
Uputative membrane protein; Similar to Clostridium acetobutylicum uncharacterized conserved protein, predicted metal-dependent enzyme, yqhq b.subtilis ortholog cac2886 SWALL:Q97F66 (EMBL:AE007786) (317 aa) fasta scores: E(): 6.8e-73, 60.39 38d in 308 aa, and to Clostridium tetani conserved protein ctc00300 SWALL:Q898Y7 (EMBL:AE015936) (249 aa) fasta scores: E(): 2.2e-65, 67.33 38d in 248 aa.
     0.981
CBO0142
Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
 
  
 0.936
tdK
Thymidine kinase; Similar to Rhodothermus sp. thymidine kinase Tdk SWALL:KITH_RHOSI (SWALL:Q9ZIG2) (213 aa) fasta scores: E(): 2.6e-34, 53.26 38d in 184 aa, and to Clostridium acetobutylicum thymidine kinase cac2887 SWALL:Q97F65 (EMBL:AE007786) (195 aa) fasta scores: E(): 5.1e-56,77.48 38d in 191 aa.
  
  
 0.831
rpmE
50S ribosomal protein L31; Binds the 23S rRNA.
     
 0.650
CBO0140
Putative membrane protein; Similar to Clostridium tetani hypothetical membrane protein ctc00303 SWALL:Q898Y4 (EMBL:AE015936) (200 aa) fasta scores: E(): 1.4e-28, 46.19 38d in 197 aa, and to Clostridium acetobutylicum predicted membrane protein cac2883 SWALL:Q97F69 (EMBL:AE007785) (192 aa) fasta scores: E(): 1.2e-26, 40.1 38d in 197 aa.
       0.615
rpiB
Similar to Escherichia coli ribose 5-phosphate isomerase B RpiB or b4090 SWALL:RPIB_ECOLI (SWALL:P37351) (149 aa) fasta scores: E(): 2.2e-27, 52.77 38d in 144 aa,and to Clostridium tetani ribose 5-phosphate isomerase ctc00307 SWALL:Q898Y0 (EMBL:AE015936) (149 aa) fasta scores: E(): 1.5e-43, 78.47 38d in 144 aa.
      0.606
CBO0865
Putative lysine decarboxylase; Belongs to the LOG family.
      0.597
atpH
ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
   0.588
CBO3073
Conserved hypothetical protein.
 
   
 0.575
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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