STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tagOSimilar to Bacillus subtilis probable undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase tago or bsu35530 SWALL:TAGO_BACSU (SWALL:O34753) (358 aa) fasta scores: E(): 7.2e-47, 41.32 id in 346 aa, and to Clostridium tetani putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase ctc00310 SWALL:Q898X7 (EMBL:AE015936) (353 aa) fasta scores: E(): 9e-86, 67.85 38d in 336 aa. (344 aa)    
Predicted Functional Partners:
mnaA
Similar to Bacillus subtilis udp-N-acetylglucosamine 2-epimerase MnaA or bsu35660 SWALL:MNAA_BACSU (SWALL:P39131) (380 aa) fasta scores: E(): 7.6e-76, 56.69 38d in 381 aa, and to Clostridium perfringens udp-N-acetylglucosamine 2-epimerase cpe2196 SWALL:Q8XIC5 (EMBL:AP003193) (384 aa) fasta scores: E(): 2.5e-107, 77.16 38d in 381 aa.
  
 0.972
tagA
Putative N-acetylmannosaminyltransferase; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
 
 
 
 0.809
rrf
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
  
 0.758
cphA
Similar to Anabaena variabilis cyanophycin synthetase CphA SWALL:CPHA_ANAVA (SWALL:O86109) (901 aa) fasta scores: E(): 5.5e-116, 39.86 38d in 868 aa, and to Clostridium tetani cyanophycin synthetase ctc00282 SWALL:Q899A3 (EMBL:AE015936) (874 aa) fasta scores: E(): 3e-189, 57.98 38d in 864 aa.
  
  
 0.757
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 
 0.734
CBO0146
Putative zinc-binding protein; Similar to Clostridium tetani comE operon protein 2 ctc00309 SWALL:Q898X8 (EMBL:AE015936) (162 aa) fasta scores: E(): 6.7e-56, 81.48 38d in 162 aa, and to Clostridium acetobutylicum deoxycytidylate deaminase cac2876 SWALL:Q97F76 (EMBL:AE007785) (162 aa) fasta scores: E(): 1.9e-44, 67.28 38d in 162 aa.
       0.728
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.709
CBO3093
Phospho-glucosyltransferase.
     
 0.692
uppS-2
Putative undecaprenyl pyrophosphate synthetase.
  
  
 0.690
CBO2982
Putative membrane protein.
 
  
 0.661
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.