Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mnaASimilar to Bacillus subtilis udp-N-acetylglucosamine 2-epimerase MnaA or bsu35660 SWALL:MNAA_BACSU (SWALL:P39131) (380 aa) fasta scores: E(): 7.6e-76, 56.69 38d in 381 aa, and to Clostridium perfringens udp-N-acetylglucosamine 2-epimerase cpe2196 SWALL:Q8XIC5 (EMBL:AP003193) (384 aa) fasta scores: E(): 2.5e-107, 77.16 38d in 381 aa. (385 aa)    
Predicted Functional Partners:
CBO3108
Putative UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
 
 0.977
tagO
Similar to Bacillus subtilis probable undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase tago or bsu35530 SWALL:TAGO_BACSU (SWALL:O34753) (358 aa) fasta scores: E(): 7.2e-47, 41.32 id in 346 aa, and to Clostridium tetani putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase ctc00310 SWALL:Q898X7 (EMBL:AE015936) (353 aa) fasta scores: E(): 9e-86, 67.85 38d in 336 aa.
  
 0.965
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.918
murA
udp-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
  0.906
murAB
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
  0.906
gtaB
UTP--glucose-1-phosphate uridylyltransferase.
  
 
 0.873
CBO0102
Similar to Escherichia coli mannose-1-phosphate guanylyltransferase manc or rfbm or rfbm1 SWALL:RFM9_ECOLI (SWALL:P37753) (471 aa) fasta scores: E(): 5.4e-36, 36.51 id in 356 aa, and to Clostridium tetani mannose-6-phosphate isomerase ctc00265 SWALL:Q899C0 (EMBL:AE015936) (355 aa) fasta scores: E(): 5.9e-94,70.33 38d in 354 aa.
    
 0.832
CBO2055
Glucose-1-phosphate thymidylyltransferase.
  
 
 0.831
CBO2718
Glucose-1-phosphate cytidylyltransferase.
    
 0.820
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.723
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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