murA protein (Clostridium botulinum A ATCC 3502)

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murA

udp-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa)

Predicted Functional Partners:

murB

0.990

glmU

0.948

mnaA

0.906

murAB

0.904

murC

0.885

murD

0.857

gtaB

0.842

CBO2718

0.828

murE

0.822

CBO2055

0.811

Your Current Organism:

Clostridium botulinum A ATCC 3502

NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBO2055	CBO2718	CBO2055	CBO2718	Glucose-1-phosphate thymidylyltransferase.	Glucose-1-phosphate cytidylyltransferase.	0.965
CBO2055	glmU	CBO2055	CBO3545	Glucose-1-phosphate thymidylyltransferase.	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.854
CBO2055	gtaB	CBO2055	CBO3112	Glucose-1-phosphate thymidylyltransferase.	UTP--glucose-1-phosphate uridylyltransferase.	0.939
CBO2055	mnaA	CBO2055	CBO0148	Glucose-1-phosphate thymidylyltransferase.	Similar to Bacillus subtilis udp-N-acetylglucosamine 2-epimerase MnaA or bsu35660 SWALL:MNAA_BACSU (SWALL:P39131) (380 aa) fasta scores: E(): 7.6e-76, 56.69 38d in 381 aa, and to Clostridium perfringens udp-N-acetylglucosamine 2-epimerase cpe2196 SWALL:Q8XIC5 (EMBL:AP003193) (384 aa) fasta scores: E(): 2.5e-107, 77.16 38d in 381 aa.	0.831
CBO2055	murA	CBO2055	CBO0159	Glucose-1-phosphate thymidylyltransferase.	udp-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.811
CBO2055	murAB	CBO2055	CBO3566	Glucose-1-phosphate thymidylyltransferase.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.811
CBO2718	CBO2055	CBO2718	CBO2055	Glucose-1-phosphate cytidylyltransferase.	Glucose-1-phosphate thymidylyltransferase.	0.965
CBO2718	glmU	CBO2718	CBO3545	Glucose-1-phosphate cytidylyltransferase.	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	0.849
CBO2718	gtaB	CBO2718	CBO3112	Glucose-1-phosphate cytidylyltransferase.	UTP--glucose-1-phosphate uridylyltransferase.	0.926
CBO2718	mnaA	CBO2718	CBO0148	Glucose-1-phosphate cytidylyltransferase.	Similar to Bacillus subtilis udp-N-acetylglucosamine 2-epimerase MnaA or bsu35660 SWALL:MNAA_BACSU (SWALL:P39131) (380 aa) fasta scores: E(): 7.6e-76, 56.69 38d in 381 aa, and to Clostridium perfringens udp-N-acetylglucosamine 2-epimerase cpe2196 SWALL:Q8XIC5 (EMBL:AP003193) (384 aa) fasta scores: E(): 2.5e-107, 77.16 38d in 381 aa.	0.820
CBO2718	murA	CBO2718	CBO0159	Glucose-1-phosphate cytidylyltransferase.	udp-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.828
CBO2718	murAB	CBO2718	CBO3566	Glucose-1-phosphate cytidylyltransferase.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.828
glmU	CBO2055	CBO3545	CBO2055	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Glucose-1-phosphate thymidylyltransferase.	0.854
glmU	CBO2718	CBO3545	CBO2718	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Glucose-1-phosphate cytidylyltransferase.	0.849
glmU	gtaB	CBO3545	CBO3112	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UTP--glucose-1-phosphate uridylyltransferase.	0.908
glmU	mnaA	CBO3545	CBO0148	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	Similar to Bacillus subtilis udp-N-acetylglucosamine 2-epimerase MnaA or bsu35660 SWALL:MNAA_BACSU (SWALL:P39131) (380 aa) fasta scores: E(): 7.6e-76, 56.69 38d in 381 aa, and to Clostridium perfringens udp-N-acetylglucosamine 2-epimerase cpe2196 SWALL:Q8XIC5 (EMBL:AP003193) (384 aa) fasta scores: E(): 2.5e-107, 77.16 38d in 381 aa.	0.918
glmU	murA	CBO3545	CBO0159	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	udp-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.948
glmU	murAB	CBO3545	CBO3566	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.947
glmU	murB	CBO3545	CBO3378	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.	0.441
glmU	murC	CBO3545	CBO3548	Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.	UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.	0.832

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