STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0177Putative RNA binding protein; Similar to Clostridium tetani transcription accessory protein ctc00330 SWALL:Q898V8 (EMBL:AE015937) (718 aa) fasta scores: E(): 7.4e-199, 77.99 38d in 718 aa. (718 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.835
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.824
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.788
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
      
 0.732
CBO0176
Aminopeptidase; Similar to Bacillus licheniformis leucine aminopeptidase precursor SWALL:Q93EJ5 (EMBL:AF358651) (449 aa) fasta scores: E(): 9.2e-10, 26.85 38d in 417 aa, and to Clostridium acetobutylicum protein containing aminopeptidase domain cac2843 SWALL:Q97F97 (EMBL:AE007782) (449 aa) fasta scores: E(): 9.1e-79, 48.59 38d in 428 aa.
  
    0.634
dnaK
Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.633
CBO1983
Conserved hypothetical protein.
  
 0.582
nnrE
Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
   
   0.542
CBO0428
Similar to Clostridium tetani hypothetical protein ctc01031 SWALL:Q896H3 (EMBL:AE015939) (222 aa) fasta scores: E(): 1.8e-19, 37.44 38d in 211 aa.
   
 0.522
CBO1138
Conserved hypothetical protein.
   
 0.522
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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