STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0183Putative pyridine nucleotide-disulphide oxidoreductase; Similar to Fusobacterium nucleatum coenzyme a disulfide reductase/ disulfide bond regulator domain fn1903 SWALL:Q8RHU1 (EMBL:AE010492) (810 aa) fasta scores: E(): 1e-163, 56.35 38d in 818 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 coenzyme a disulfide reductase/ disulfide bond regulator domain fnv2089 SWALL:Q7P7P1 (EMBL:AABF01000012) (809 aa) fasta scores: E(): 2.7e-159, 55.5 38d in 818 aa; Belongs to the sulfur carrier protein TusA family. (817 aa)    
Predicted Functional Partners:
CBO1505
Putative oxidoreductase.
  
 
 0.917
CBO0521
Superoxide dismutase [fe].
  
 
 0.896
CBO2277
Putative superoxide dismutase [Mn/Fe]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.896
iscS
Cysteine desulfurase.
   
 
 0.895
iscS-2
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 
 0.895
CBO0182
ArsR-family transcriptional regulator; Similar to Bacillus anthracis transcriptional repressor PagR or TcrA or Pxo1-109 SWALL:PAGR_BACAN (SWALL:O31178) (99 aa) fasta scores: E(): 8e-09, 41.37 38d in 87 aa, and to Bacillus cereus transcriptional regulator, ArsR family bc4256 SWALL:Q818J4 (EMBL:AE017011) (96 aa) fasta scores: E(): 4.6e-16, 63.09 38d in 84 aa.
 
  
 0.857
CBO3246
Conserved hypothetical protein.
  
  
 0.855
CBO1576
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
  
  
 0.841
CBO2574
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
  
  
 0.841
CBO1580
Putative oxidoreductase.
  
  
 0.840
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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