STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBO0185Putative guanosine 3',5'-bis-pyrophosphate (ppGpp) synthesis/degradation protein; Similar to Clostridium tetani GTP pyrophosphokinase ctc00336 SWALL:Q898V3 (EMBL:AE015937) (262 aa) fasta scores: E(): 8.5e-70, 77.86 38d in 262 aa. (262 aa)    
Predicted Functional Partners:
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.917
CBO0191
Putative adenylate cyclase; Similar to Clostridium acetobutylicum adenilate cyclase, class2 cac0650 SWALL:Q97LB2 (EMBL:AE007580) (180 aa) fasta scores: E(): 8.5e-37, 64.77 38d in 176 aa, and to Clostridium perfringens hypothetical protein Cpe1352 cpe1352 SWALL:Q8XKP2 (EMBL:AP003190) (187 aa) fasta scores: E(): 6.5e-36, 62.92 38d in 178 aa.
  
  
  0.912
nrdD
Similar to Escherichia coli anaerobic ribonucleoside-triphosphate reductase NrdD or b4238 SWALL:NRDD_ECOLI (SWALL:P28903) (712 aa) fasta scores: E(): 3.3e-50, 32.23 38d in 726 aa, and to Clostridium acetobutylicum oxygen-sensitive ribonucleoside-triphosphate reductase NrdD cac0480 SWALL:Q97LS4 (EMBL:AE007562) (702 aa) fasta scores: E(): 1.2e-139, 74.07 38d in 706 aa.
     
  0.900
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
  0.900
folE
Putative GTP cyclohydrolase I.
     
  0.800
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.800
ribA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
  0.800
CBO0184
Conserved hypothetical protein; Similar to Clostridium acetobutylicum uncharacterized conserved protein cac0641 SWALL:Q97LC1 (EMBL:AE007579) (264 aa) fasta scores: E(): 2.5e-49,52.98 38d in 251 aa.
 
     0.770
trmE
Probable tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
    0.612
gidA
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
   
    0.587
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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