STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0189DnaJ-related protein; Similar to Clostridium acetobutylicum molecular chaperone, DNAJ family cac0648 SWALL:Q97LB4 (EMBL:AE007580) (195 aa) fasta scores: E(): 1.6e-36,55.15 38d in 194 aa. (199 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.988
CBO0190
Conserved hypothetical protein; Similar to Clostridium acetobutylicum uncharacterized protein, homolog of thermotoga maritima cac0649 SWALL:Q97LB3 (EMBL:AE007580) (283 aa) fasta scores: E(): 6.7e-52, 52.51 38d in 278 aa, and to Thermotoga maritima hypothetical protein Tm1805 tm1805 SWALL:Q9X2C5 (EMBL:AE001818) (272 aa) fasta scores: E(): 1.4e-10, 35.03 38d in 294 aa.
 
     0.954
CBO0188
Putative membrane protein; Similar to Staphylococcus epidermidis cell shape determinant MreD se1331 SWALL:Q8CNZ6 (EMBL:AE016748) (173 aa) fasta scores: E(): 0.34, 22.36 38d in 161 aa, and to Clostridium tetani heptaprenyl diphosphate synthase component I ctc01025 SWALL:Q896H9 (EMBL:AE015939) (181 aa) fasta scores: E(): 0.13, 25.97 38d in 154 aa.
 
    0.950
hymB
Putative electron-transferring subunit of iron-only hydrogenase.
  
 0.949
grpE
Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...]
 
 
 0.947
htpG
Chaperone protein; Molecular chaperone. Has ATPase activity.
  
 0.938
CBO0191
Putative adenylate cyclase; Similar to Clostridium acetobutylicum adenilate cyclase, class2 cac0650 SWALL:Q97LB2 (EMBL:AE007580) (180 aa) fasta scores: E(): 8.5e-37, 64.77 38d in 176 aa, and to Clostridium perfringens hypothetical protein Cpe1352 cpe1352 SWALL:Q8XKP2 (EMBL:AP003190) (187 aa) fasta scores: E(): 6.5e-36, 62.92 38d in 178 aa.
 
     0.874
nifJ1
Putative pyruvate-flavodoxin oxidoreductase; Also similar to CBO2760 (65.74 38d).
   
 0.868
groEL
60 kDa chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.865
CBO1505
Putative oxidoreductase.
   
 0.795
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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