STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0199Conserved hypothetical membrane; Similar to Clostridium acetobutylicum CBS domains cac0678 SWALL:Q97L84 (EMBL:AE007583) (142 aa) fasta scores: E(): 4e-24, 54.81 38d in 135 aa, and to Clostridium tetani inosine-5-monophosphate dehydrogenase related protein ctc00347 SWALL:Q898U3 (EMBL:AE015937) (143 aa) fasta scores: E(): 4.3e-25, 57.97 38d in 138 aa. (138 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
 
 
 0.800
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.758
rpsM
30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
  
 
 0.688
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
  
   0.682
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
  
   0.675
rpsJ
30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
 
 
   0.674
pssA
Similar to Bacillus subtilis CDP-diacylglycerol--serine O-phosphatidyltransferase PssA or Pss or bsu02270 SWALL:PSS_BACSU (SWALL:P39823) (177 aa) fasta scores: E(): 5.7e-17, 39.15 38d in 166 aa, and to Clostridium tetani CDP-diacylglycerol--serine O-phosphatidyltransferase ctc00346 SWALL:Q898U4 (EMBL:AE015937) (175 aa) fasta scores: E(): 3.4e-45,70.17 38d in 171 aa; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
     0.670
rpsB
30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
   
   0.669
purL
Formylglycinamidine ribonucleotide synthetase.
  
  
 0.658
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.655
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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