STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0210NAD-dependent malic enzyme; Similar to Bacillus stearothermophilus NAD-dependent malic enzyme SWALL:MAOX_BACST (SWALL:P16468) (478 aa) fasta scores: E(): 7e-79, 59.38 38d in 389 aa,and to Clostridium tetani NAD-dependent malic enzyme ctc00356 SWALL:Q898T6 (EMBL:AE015937) (389 aa) fasta scores: E(): 6.1e-102, 73.52 38d in 389 aa; Also similar to CBO0246 (66.6 38d). (390 aa)    
Predicted Functional Partners:
pykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.971
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.968
ppdK
Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
  
 
 0.967
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 0.959
nifJ1
Putative pyruvate-flavodoxin oxidoreductase; Also similar to CBO2760 (65.74 38d).
  
 
 0.951
nifJ2
Pyruvate-flavodoxin oxidoreductase; Also similar to CBO1192 (65.74 38d).
  
 
 0.948
fumA
Fumarate hydratase, subunit B; Similar to C-terminal region of Escherichia coli fumarate hydratase class I, anaerobic FumB or b4122 SWALL:FUMB_ECOLI (SWALL:P14407) (548 aa) fasta scores: E(): 4.1e-18, 38.76 38d in 178 aa.
 
 
 0.947
ptA
Phosphate acetyltransferase.
 
 
  
 0.932
fumA-2
Similar to N-terminal region of Escherichia coli fumarate hydratase class I, anaerobic FumB or b4122 SWALL:FUMB_ECOLI (SWALL:P14407) (548 aa) fasta scores: E(): 3.7e-09, 35.62 38d in 233 aa.
  
 
 0.922
ldhA1
Putative acetyltransferase (pseudogene); Pfam match to entry PF00583 Acetyltransf,Acetyltransferase (GNAT) family, score 28.4, E-value 4.9e-09; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.909
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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