STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
splBSimilar to Bacillus subtilis spore photoproduct lyase SplB or Spl or bsu13930 SWALL:SPL_BACSU (SWALL:P37956) (342 aa) fasta scores: E(): 1.4e-52, 45.23 id in 336 aa, and to Clostridium acetobutylicum spore photoproduct lyase, SplB cac0699 SWALL:Q97L63 (EMBL:AE007585) (336 aa) fasta scores: E(): 4.5e-71,54.92 38d in 335 aa. (335 aa)    
Predicted Functional Partners:
gpr
Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
   
 0.825
miaB
Putative radical SAM superfamily protein; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
     
 0.759
trmL
Putative RNA methylase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.618
yyaC
Conserved hypothetical protein; Similar to Clostridium acetobutylicum spore protease gpr related protein, yyac b.subtilis ortholog cac2857 SWALL:Q97F84 (EMBL:AE007783) (188 aa) fasta scores: E(): 4e-36, 59.06 38d in 171 aa.
  
   
 0.615
yyaC-2
Conserved hypothetical protein.
  
   
 0.583
ytaF
Putative membrane protein; Probably functions as a manganese efflux pump.
  
     0.500
CBO0215
Putative exported protein; Similar to Clostridium acetobutylicum uncharacterized conserved protein, vanw of enterococcus faecalis related cac0691 SWALL:Q97L71 (EMBL:AE007584) (411 aa) fasta scores: E(): 3.4e-55, 42.72 38d in 433 aa, and to Clostridium tetani vancomycin b-type resistance protein vanw vanw or ctc00360 SWALL:Q898T2 (EMBL:AE015937) (467 aa) fasta scores: E(): 7.3e-69, 45.59 38d in 454 aa; Also similar to the upstream CDS, CBO0214 (48 38d) and CBO0820 (47 38d).
       0.496
CBO0218
Conserved hypothetical protein; Similar to Clostridium tetani degv protein degv or ctc00368 SWALL:Q898S4 (EMBL:AE015937) (280 aa) fasta scores: E(): 1.1e-66, 65.71 38d in 280 aa, and to Clostridium acetobutylicum hypothetical upf0230 protein Cac0701 SWALL:Y701_CLOAB (SWALL:Q97L61) (279 aa) fasta scores: E(): 5.9e-59, 60.21 38d in 279 aa.
       0.480
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.476
CBO0775
Putative membrane protein.
  
     0.446
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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