STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
trmLPutative RNA methylase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (155 aa)    
Predicted Functional Partners:
CBO0218
Conserved hypothetical protein; Similar to Clostridium tetani degv protein degv or ctc00368 SWALL:Q898S4 (EMBL:AE015937) (280 aa) fasta scores: E(): 1.1e-66, 65.71 38d in 280 aa, and to Clostridium acetobutylicum hypothetical upf0230 protein Cac0701 SWALL:Y701_CLOAB (SWALL:Q97L61) (279 aa) fasta scores: E(): 5.9e-59, 60.21 38d in 279 aa.
  
    0.770
splB
Similar to Bacillus subtilis spore photoproduct lyase SplB or Spl or bsu13930 SWALL:SPL_BACSU (SWALL:P37956) (342 aa) fasta scores: E(): 1.4e-52, 45.23 id in 336 aa, and to Clostridium acetobutylicum spore photoproduct lyase, SplB cac0699 SWALL:Q97L63 (EMBL:AE007585) (336 aa) fasta scores: E(): 4.5e-71,54.92 38d in 335 aa.
       0.618
CBO1505
Putative oxidoreductase.
     
 0.564
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
 
    0.544
CBO0219
Putative lipoprotein; Similar to Listeria monocytogenes cd4+ T cell-stimulating antigen precursor tcsa or lmo1388 SWALL:TCSA_LISMO (SWALL:Q48754) (357 aa) fasta scores: E(): 1.4e-30, 41.09 38d in 365 aa, and to Clostridium tetani membrane lipoprotein TmpC precursor TmpC or ctc00369 SWALL:Q898S3 (EMBL:AE015937) (359 aa) fasta scores: E(): 2e-65, 56.09 38d in 369 aa.
       0.543
rlmH
Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
  
   
 0.532
rsmB
Putative ribosomal RNA methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.530
nnrE
Putative carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
     
 0.485
rrf
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
   
    0.484
rpoN
Similar to Alcaligenes eutrophus RNA polymerase sigma-54 factor RpoN or NtrA or Hno SWALL:RP54_ALCEU (SWALL:P28615) (493 aa) fasta scores: E(): 6.6e-36, 33.6 id in 494 aa, and to Clostridium tetani RNA polymerase sigma-54 factor RpoN or ctc00376 SWALL:Q898R6 (EMBL:AE015937) (461 aa) fasta scores: E(): 2.6e-87,60.47 38d in 463 aa.
 
     0.444
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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