STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBO0219Putative lipoprotein; Similar to Listeria monocytogenes cd4+ T cell-stimulating antigen precursor tcsa or lmo1388 SWALL:TCSA_LISMO (SWALL:Q48754) (357 aa) fasta scores: E(): 1.4e-30, 41.09 38d in 365 aa, and to Clostridium tetani membrane lipoprotein TmpC precursor TmpC or ctc00369 SWALL:Q898S3 (EMBL:AE015937) (359 aa) fasta scores: E(): 2e-65, 56.09 38d in 369 aa. (367 aa)    
Predicted Functional Partners:
CBO0220
ABC-transporter, ATP-binding protein; Similar to Clostridium acetobutylicum sugar ABC-transporter, ATP-ase component cac0703 SWALL:Q97L59 (EMBL:AE007585) (514 aa) fasta scores: E(): 1.5e-128,75.78 38d in 508 aa.
 
 
 0.995
CBO0222
Similar to Clostridium acetobutylicum sugar ABC transporter, permease protein cac0705 SWALL:Q97L57 (EMBL:AE007585) (310 aa) fasta scores: E(): 5.9e-82,70.64 38d in 310 aa; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.993
CBO0221
Similar to Clostridium acetobutylicum sugar ABC transporter, permease protein cac0704 SWALL:Q97L58 (EMBL:AE007585) (365 aa) fasta scores: E(): 1.9e-88,64.94 38d in 368 aa; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.989
spoIIGA
Putative sporulation sigma-E factor processing peptidase.
   
    0.582
trmL
Putative RNA methylase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.543
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
     
 0.503
pdp
Pyrimidine-nucleoside phosphorylase.
     
 0.461
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.447
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.444
CBO0218
Conserved hypothetical protein; Similar to Clostridium tetani degv protein degv or ctc00368 SWALL:Q898S4 (EMBL:AE015937) (280 aa) fasta scores: E(): 1.1e-66, 65.71 38d in 280 aa, and to Clostridium acetobutylicum hypothetical upf0230 protein Cac0701 SWALL:Y701_CLOAB (SWALL:Q97L61) (279 aa) fasta scores: E(): 5.9e-59, 60.21 38d in 279 aa.
  
    0.443
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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