STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cggRSimilar to Bacillus megaterium central glycolytic genes regulator CggR SWALL:CGGR_BACME (SWALL:P35168) (342 aa) fasta scores: E(): 8.9e-45, 43.49 38d in 338 aa, and to Thermoanaerobacter tengcongensis transcriptional regulator, contains sigma factor-related N-terminal domain DeoR2 or tte1763 SWALL:Q8R963 (EMBL:AE013129) (340 aa) fasta scores: E(): 1e-59, 55.58 38d in 340 aa. (343 aa)    
Predicted Functional Partners:
gap1
Similar to Bacillus megaterium glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_BACME (SWALL:P23722) (334 aa) fasta scores: E(): 4.3e-78, 64.86 id in 333 aa, and to Bacillus stearothermophilus glyceraldehyde 3-phosphate dehydrogenase Gap SWALL:G3P_BACST (SWALL:P00362) (334 aa) fasta scores: E(): 4.1e-82, 69.06 38d in 333 aa; Also similar to CBO1095 (66.26 38d).
  
  
 0.755
pgK
Phosphoglycerate kinase; Similar to Bacillus megaterium phosphoglycerate kinase Pgk SWALL:PGK_BACME (SWALL:P24269) (394 aa) fasta scores: E(): 2.4e-80, 57.07 38d in 396 aa, and to Clostridium acetobutylicum phosphoglycerate kinase Pgk or cac0710 SWALL:PGK_CLOAB (SWALL:O52632) (397 aa) fasta scores: E(): 5.4e-110, 77.44 38d in 399 aa.
     
 0.644
rpoN
Similar to Alcaligenes eutrophus RNA polymerase sigma-54 factor RpoN or NtrA or Hno SWALL:RP54_ALCEU (SWALL:P28615) (493 aa) fasta scores: E(): 6.6e-36, 33.6 id in 494 aa, and to Clostridium tetani RNA polymerase sigma-54 factor RpoN or ctc00376 SWALL:Q898R6 (EMBL:AE015937) (461 aa) fasta scores: E(): 2.6e-87,60.47 38d in 463 aa.
 
     0.623
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.568
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.563
purR
Pur operon repressor.
  
   
 0.473
gapA2
Glyceraldehyde 3-phosphate dehydrogenase A; Also similar to CBO0226 (66.26 38d); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.471
CBO0116
Conserved hypothetical protein; Similar to Bacillus subtilis Veg protein or bsu00440 SWALL:VEG_BACSU (SWALL:P37466) (86 aa) fasta scores: E(): 5.9e-12, 52.77 38d in 72 aa, and to Clostridium acetobutylicum uncharacterized protein, Veg b.subtilis ortholog cac2904 SWALL:Q97F49 (EMBL:AE007788) (78 aa) fasta scores: E(): 3.2e-18, 69.73 38d in 76 aa.
  
     0.467
secG
Probable protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
 
     0.454
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
  
 0.437
Your Current Organism:
Clostridium botulinum A ATCC 3502
NCBI taxonomy Id: 413999
Other names: C. botulinum A str. ATCC 3502, Clostridium botulinum A str. ATCC 3502, Clostridium botulinum A strain ATCC 3502
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